School of Health and Rehabilitation Sciences, The University of Queensland, St Lucia, Brisbane, QLD, 4072, Australia.
Centre for Functioning and Health Research, Metro South Health, Brisbane, Australia.
Dysphagia. 2023 Feb;38(1):1-22. doi: 10.1007/s00455-022-10443-3. Epub 2022 Apr 20.
Oropharyngeal dysphagia is common post-stroke and can have serious consequences for patients. Understanding dysphagia recovery is critically important to inform prognostication and support patients and professionals with care planning. This systematic review was undertaken to identify clinical predictors of dysphagia recovery post-stroke. Online databases (EMBASE, Scopus, Web of Science, PubMed, CINAHL, and Cochrane) were searched for studies reporting longitudinal swallowing recovery in adults post-stroke. Dysphagia recovery was defined as improvement measured on a clinical swallowing scale or upgrade in oral and/or enteral feeding status by the end of the follow-up period. The search strategy returned 6598 studies from which 87 studies went through full-text screening, and 19 studies were included that met the eligibility criteria. Age, airway compromise identified on instrumental assessment, dysphagia severity, bilateral lesions, and stroke severity were identified as predictors of persistent dysphagia and negative recovery in multiple logistic regression analysis. The available literature was predominated by retrospective data, and comparison of outcomes was limited by methodological differences across the studies in terms of the choice of assessment, measure of recovery, and period of follow-up. Future prospective research is warranted with increased representation of haemorrhagic strokes and uniform use of standardized scales of swallowing function.
口咽吞咽障碍是脑卒中后的常见并发症,可对患者造成严重后果。了解吞咽障碍的恢复情况对于预后判断以及为患者和医护人员的照护计划提供支持至关重要。本系统评价旨在确定脑卒中后吞咽障碍恢复的临床预测因素。在线数据库(EMBASE、Scopus、Web of Science、PubMed、CINAHL 和 Cochrane)检索了报告成人脑卒中后吞咽恢复的纵向研究。吞咽障碍恢复定义为在随访期末,通过临床吞咽量表评估或经口/肠内喂养状态升级来衡量的改善。该检索策略共返回 6598 项研究,其中 87 项研究经过全文筛选,19 项研究符合纳入标准。在多变量逻辑回归分析中,年龄、仪器评估发现的气道受损、吞咽障碍严重程度、双侧病变和卒中严重程度被确定为持续性吞咽障碍和不良恢复的预测因素。现有文献主要为回顾性数据,由于研究之间在评估选择、恢复衡量以及随访时间等方面存在方法学差异,因此对结果的比较受到限制。未来需要开展前瞻性研究,增加对出血性卒中的代表性,并统一使用标准化的吞咽功能量表。