Yu H C, Ketabchi M
Acta Cytol. 1987 Jan-Feb;31(1):73-6.
A case of malignant amelanotic melanoma of the uterine cervix in a patient presenting with right hemiparesis and enlarged lymph nodes was diagnosed in Papanicolaou-stained cervical smears showing many melanoma cells. Melanoma cells with bizzare nuclear and cytoplasmic abnormalities, rarely seen in other tumors, helped to establish a positive diagnosis. The diagnosis was confirmed by histopathologic study of the endocervical surgical specimen, including a positive immunoperoxidase staining for S-100 protein.
一名子宫颈恶性无黑色素黑色素瘤患者，表现为右半身轻瘫和淋巴结肿大，在巴氏染色的宫颈涂片上发现许多黑色素瘤细胞，从而得以诊断。黑色素瘤细胞具有奇异的核和胞质异常，在其他肿瘤中很少见，这有助于做出阳性诊断。通过宫颈手术标本的组织病理学研究证实了诊断，包括S-100蛋白免疫过氧化物酶染色阳性。
