Department of Geology and Geophysics, Texas A&M University, College Station, TX, USA.
Department of Geology and Geophysics, Texas A&M University, College Station, TX, USA.
Environ Res. 2022 Sep;212(Pt B):113307. doi: 10.1016/j.envres.2022.113307. Epub 2022 Apr 18.
Pb isotope ratios are used for apportioning the sources of Pb in the blood of children (ages 1-6) screened for high blood Pb levels (>5 μg/dL) surrounding urban areas of Kansas City, MO. We compared Pb isotope ratios measured in the child's blood with those of the most likely sources of Pb in that child's home environment. The environmental sources sampled consisted of topsoils, paints, occupational sources (e.g., oil rig workers' uniforms, mechanics' clothes), indoor air filters, dusts, and dietary sources (e.g., spices). Blood lead levels (BLL) ranged from 2.9 to 12.7 μg/dL in children from the five homes participating in this study. Measurements of Pb/Pb, Pb/Pb and Pb/Pb isotope ratios were made by multi-collector ICP-MS. Comparison of the Pb isotope ratios in home environment samples versus those in the child's blood in each home allowed the identification of possible sources of a child's Pb exposure in three homes. In five homes investigated, children's blood Pb levels were most likely to be derived from dusts inside, and topsoil outside, the homes, or a mixture thereof. In one case, blood Pb was derived from turmeric spice and, in another, the Pb was derived from paint. It is not always possible to directly link high BLLs to the environmental sources collected when Pb isotope ratios of the environmental samples did not overlap with those of the blood.
我们比较了儿童血液中的 Pb 同位素比值与该儿童家庭环境中最有可能的 Pb 源的 Pb 同位素比值。采样的环境源包括表土、油漆、职业源（例如，石油钻井工人的制服、机械师的衣服）、室内空气过滤器、灰尘和饮食源（例如，香料）。参与这项研究的五个家庭中，儿童的血铅水平（BLL）范围从 2.9 到 12.7μg/dL。通过多收集器 ICP-MS 测量 Pb/Pb、Pb/Pb 和 Pb/Pb 同位素比值。比较每个家庭中环境样本与儿童血液中的 Pb 同位素比值，可确定三个家庭中儿童 Pb 暴露的可能来源。在所调查的五个家庭中，儿童血液中的 Pb 水平最有可能来自家庭内部的灰尘和外部的表土，或者两者的混合物。在一种情况下，血铅来自姜黄香料，而在另一种情况下，铅来自油漆。当环境样本的 Pb 同位素比值与血液中的 Pb 同位素比值没有重叠时，并不总是能够将高 BLL 直接与收集的环境源联系起来。
