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使用便携式近红外光谱仪通过血红蛋白浓度变化进行压力评估

Stress Evaluation by Hemoglobin Concentration Change Using Mobile NIRS.

作者信息

Takahashi Shingo, Sakurai Noriko, Kasai Satoshi, Kodama Naoki

机构信息

Department of Healthcare Informatics, Faculty of Health and Welfare, Takasaki University of Health and Welfare, 37-1 Nakaorui-machi, Takasaki 370-0033, Japan.

Department of Radiological Technology, Faculty of Medical Technology, Niigata University of Health and Welfare, 1398 Shimami-cho, Kita-ku, Niigata 950-3198, Japan.

出版信息

Brain Sci. 2022 Apr 11;12(4):488. doi: 10.3390/brainsci12040488.

DOI:10.3390/brainsci12040488
PMID:35448019
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9025147/
Abstract

Previous studies have reported a relationship between stress and brain activity, and stress has been quantitatively evaluated using near-infrared spectroscopy (NIRS). In the present study, we examined whether a relationship exists between salivary amylase levels and brain activity during the trail-making test (TMT) using mobile NIRS. This study aimed to assess stress levels by using mobile NIRS. Salivary amylase was measured with a salivary amylase monitor, and hemoglobin concentration was measured using Neu's HOT-2000. Measurements were taken four times for each subject, and the values at each measurement were evaluated. Changes in the values at the first-second, second-third, and third-fourth measurements were also analyzed. Results showed that the value of the fluctuations has a higher correlation than the comparison of point values. These results suggest that the accuracy of stress assessment by NIRS can be improved by using variability and time-series data compared with stress assessment using NIRS at a single time point.

摘要

先前的研究报告了压力与大脑活动之间的关系,并且已经使用近红外光谱法(NIRS)对压力进行了定量评估。在本研究中,我们使用便携式近红外光谱仪,研究了在连线测验(TMT)期间唾液淀粉酶水平与大脑活动之间是否存在关系。本研究旨在通过使用便携式近红外光谱仪评估压力水平。使用唾液淀粉酶监测仪测量唾液淀粉酶,并使用Neu's HOT-2000测量血红蛋白浓度。对每个受试者进行了四次测量,并对每次测量的值进行了评估。还分析了第一次-第二次、第二次-第三次和第三次-第四次测量值的变化。结果表明,波动值的相关性高于点值比较。这些结果表明,与在单个时间点使用近红外光谱仪进行压力评估相比,通过使用变异性和时间序列数据,可以提高近红外光谱仪压力评估的准确性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b852/9025147/83931c74b95e/brainsci-12-00488-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b852/9025147/95d127f98a8c/brainsci-12-00488-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b852/9025147/11dee0fd5aa5/brainsci-12-00488-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b852/9025147/bbd6ccc0c53d/brainsci-12-00488-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b852/9025147/7f9289da9c5e/brainsci-12-00488-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b852/9025147/85cf53bdeb70/brainsci-12-00488-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b852/9025147/246eae99bbe1/brainsci-12-00488-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b852/9025147/fcf7e44d70ca/brainsci-12-00488-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b852/9025147/83931c74b95e/brainsci-12-00488-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b852/9025147/95d127f98a8c/brainsci-12-00488-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b852/9025147/11dee0fd5aa5/brainsci-12-00488-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b852/9025147/bbd6ccc0c53d/brainsci-12-00488-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b852/9025147/7f9289da9c5e/brainsci-12-00488-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b852/9025147/85cf53bdeb70/brainsci-12-00488-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b852/9025147/246eae99bbe1/brainsci-12-00488-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b852/9025147/fcf7e44d70ca/brainsci-12-00488-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b852/9025147/83931c74b95e/brainsci-12-00488-g008.jpg

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Front Hum Neurosci. 2021 Jul 1;15:663463. doi: 10.3389/fnhum.2021.663463. eCollection 2021.
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Salivary Alpha-Amylase as a Biomarker of Stress in Behavioral Medicine.唾液α-淀粉酶作为行为医学应激的生物标志物。
Int J Behav Med. 2020 Jun;27(3):337-342. doi: 10.1007/s12529-019-09843-x.
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Relationship Between Cerebral Blood Oxygenation and Electrical Activity During Mental Stress Tasks: Simultaneous Measurements of NIRS and EEG.
精神应激任务时脑血氧与脑电活动的关系:NIRS 与 EEG 的同步测量。
Adv Exp Med Biol. 2020;1232:99-104. doi: 10.1007/978-3-030-34461-0_14.
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Biomarkers in Stress Related Diseases/Disorders: Diagnostic, Prognostic, and Therapeutic Values.应激相关疾病/障碍中的生物标志物:诊断、预后及治疗价值
Front Mol Biosci. 2019 Oct 18;6:91. doi: 10.3389/fmolb.2019.00091. eCollection 2019.
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