Ji Xingkai, Zhang Hao, Zang Lianru, Yan Shengjie, Wu Xiaomei
Centre for Biomedical Engineering, School of Information Science and Technology, Fudan University, Shanghai 200433, China.
Academy for Engineering and Technology, Fudan University, Shanghai 200433, China.
J Cardiovasc Dev Dis. 2022 Mar 24;9(4):95. doi: 10.3390/jcdd9040095.
At present, the effects of discharge modes of multielectrode catheters on the distribution of pulsed electric fields have not been completely clarified. Therefore, the control of the distribution of the pulsed electric field by selecting the discharge mode remains one of the key technical problems to be solved.
We constructed a model including myocardium, blood, and a flower catheter. Subsequently, by setting different positive and ground electrodes, we simulated the electric field distribution in the myocardium of four discharge modes (A, B, C, and D) before and after the catheter rotation and analyzed their mechanisms.
Modes B, C, and D formed a continuous circumferential ablation lesion without the rotation of the catheter, with depths of 1.6 mm, 2.7 mm, and 0.7 mm, respectively. After the catheter rotation, the four modes could form a continuous circumferential ablation lesion with widths of 10.8 mm, 10.6 mm, 11.8 mm, and 11.5 mm, respectively, and depths of 5.2 mm, 2.7 mm, 4.7 mm, and 4.0 mm, respectively.
The discharge mode directly affects the electric field distribution in the myocardium. Our results can help improve PFA procedures and provide enlightenment for the design of the discharge mode with multielectrode catheters.
目前，多电极导管的放电模式对脉冲电场分布的影响尚未完全阐明。因此，通过选择放电模式来控制脉冲电场分布仍然是有待解决的关键技术问题之一。
我们构建了一个包含心肌、血液和花形导管的模型。随后，通过设置不同的正电极和接地电极，模拟了导管旋转前后四种放电模式（A、B、C和D）在心肌中的电场分布，并分析其机制。
模式B、C和D在导管不旋转的情况下形成了连续的环形消融灶，深度分别为1.6毫米、2.7毫米和0.7毫米。导管旋转后，四种模式均可形成连续的环形消融灶，宽度分别为10.8毫米、10.6毫米、11.8毫米和11.5毫米，深度分别为5.2毫米、2.7毫米、4.7毫米和4.0毫米。
放电模式直接影响心肌中的电场分布。我们的结果有助于改进脉冲电场消融手术，并为多电极导管放电模式的设计提供启示。
