公牛精液生产性状的候选基因：信息学方法综述
Candidate Genes in Bull Semen Production Traits: An Information Approach Review.
作者信息
Modiba Mamokoma Cathrine, Nephawe Khathutshelo Agree, Mdladla Khanyisile Hadebe, Lu Wenfa, Mtileni Bohani
机构信息
College of Animal Sciences and Technology, Jilin Agricultural University, Xincheng Street, Changchun 130118, China.
Joint Laboratory of Modern Agriculture Technology International Cooperation Ministry of Education, Jilin Agricultural University, Changchun 130118, China.
出版信息
Vet Sci. 2022 Mar 23;9(4):155. doi: 10.3390/vetsci9040155.
Semen quality plays a crucial role in the successful implementation of breeding programs, especially where artificial insemination (AI) is practiced. Bulls with good semen traits have good fertility and can produce a volume of high semen per ejaculation. The aim of this review is to use an information approach to highlight candidate genes and their relation to bull semen production traits. The use of genome-wide association studies (GWAS) has been demonstrated to be successful in identifying genomic regions and individual variations associated with production traits. Studies have reported over 40 genes associated with semen traits using Illumina BeadChip single-nucleotide polymorphism (SNPs).
精液质量在育种计划的成功实施中起着至关重要的作用，尤其是在采用人工授精（AI）的情况下。具有良好精液特性的公牛具有良好的生育能力，每次射精可产生大量优质精液。本综述的目的是采用信息学方法来突出候选基因及其与公牛精液生产性状的关系。全基因组关联研究（GWAS）已被证明在识别与生产性状相关的基因组区域和个体变异方面是成功的。已有研究报告使用Illumina BeadChip单核苷酸多态性（SNP）鉴定出40多个与精液性状相关的基因。
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