Department of Medical Imaging, Chi Mei Medical Center, 901, Chung-Hwa Road, Yung-Kang, Tainan, 710, Taiwan.
Department of Pathology, Chi Mei Medical Center, Tainan, Taiwan.
J Med Case Rep. 2022 Apr 22;16(1):168. doi: 10.1186/s13256-022-03394-8.
Renal adenomatosis is a rare disease that presents as multiple papillary adenomas in the bilateral kidneys. Moreover, papillary adenoma is considered a precursor to papillary renal cell carcinoma. Therefore, patients with renal adenomatosis may have higher risk of developing malignancy than patients without this benign condition.
We present the case of a 62-year-old Asian woman with past history of papillary thyroid cancer. She underwent contrast-enhanced magnetic resonance imaging of the abdomen to screen for metastasis in 2010 and was followed up with computed tomography or magnetic resonance imaging annually. She was found to have a right renal tumor on computed tomography and underwent partial nephrectomy. The pathological diagnosis of the right renal tumor was angiomyolipoma. Renal adenomatosis was also histologically confirmed in the renal parenchyma adjacent to the angiomyolipoma. In this case report, we demonstrate the natural course of renal adenomatosis over 10 years using imaging studies. The benign tumors gradually progressed during the follow-up period. Larger tumor sizes and more hypoenhanced nodules in the bilateral kidneys were observed on follow-up computed tomography and magnetic resonance imaging.
Due to its malignant potential, the clinical course of renal adenomatosis must be monitored. We present the natural course of renal adenomatosis with magnetic resonance imaging during a 10-year follow-up period.
肾腺瘤病是一种罕见的疾病，表现为双侧肾脏多发性乳头状腺瘤。此外，乳头状腺瘤被认为是乳头状肾细胞癌的前兆。因此，肾腺瘤病患者发生恶性肿瘤的风险可能高于没有这种良性疾病的患者。
我们报告了一位 62 岁的亚洲女性病例，她有甲状腺乳头状癌病史。她于 2010 年接受腹部增强磁共振成像筛查转移，并每年进行计算机断层扫描或磁共振成像随访。她在计算机断层扫描中发现右侧肾脏有肿瘤，并进行了部分肾切除术。右侧肾脏肿瘤的病理诊断为血管平滑肌脂肪瘤。在血管平滑肌脂肪瘤旁的肾实质中也组织学证实了肾腺瘤病。在本病例报告中，我们通过影像学研究展示了肾腺瘤病 10 多年的自然病程。在随访期间，良性肿瘤逐渐进展。在后续的计算机断层扫描和磁共振成像中，观察到双侧肾脏的肿瘤大小更大，低增强结节更多。
由于其恶性潜能，必须监测肾腺瘤病的临床病程。我们通过 10 年的磁共振成像随访，展示了肾腺瘤病的自然病程。
