一株新型黑曲霉 victorivirus 的全基因组序列
Complete genome sequence of a novel victorivirus infecting Aspergillus niger.
机构信息
Key Laboratory of Endemic and Ethnic Diseases (Guizhou Medical University), Ministry of Education, Guiyang, 550004, China.
Key Laboratory of Medical Molecular Biology (Guizhou Medical University), Guizhou Province, Guiyang, 550004, China.
出版信息
Arch Virol. 2022 Jun;167(6):1475-1479. doi: 10.1007/s00705-022-05441-7. Epub 2022 Apr 21.
Aspergillus niger is an important filamentous phytopathogenic fungus with a broad host range. A novel double-stranded (ds) RNA mycovirus, named Aspergillus niger victorivirus 1 (AnV1), isolated from A. niger strain baiyun3.23-4, was sequenced and analyzed. The AnV1 genome is 5317 nucleotides long with a GC content of 56%. AnV1 contains two open reading frames (ORF1 and 2), overlapping at a tetranucleotide sequence (AUGA). ORF1 encodes a putative capsid protein (CP) of 778 amino acids (aa), while ORF2 potentially encodes a putative RNA-dependent RNA polymerase (RdRp) of 826 aa. Phylogenetic analysis indicated that AnV1 is a new member of the genus Victorivirus in the family Totiviridae. As far as we know, this is the first report of the complete genome sequence of a victorivirus infecting A. niger.
黑曲霉是一种重要的丝状植物病原真菌，宿主范围广泛。从黑曲霉菌株 baiyun3.23-4 中分离到一种新型双链 (ds) RNA 真菌病毒，命名为黑曲霉维多利尔病毒 1（AnV1），并对其进行了测序和分析。AnV1 基因组长 5317 个核苷酸，GC 含量为 56%。AnV1 包含两个开放阅读框（ORF1 和 2），在一个四核苷酸序列（AUGA）处重叠。ORF1 编码一个推定的衣壳蛋白（CP），由 778 个氨基酸（aa）组成，而 ORF2 可能编码一个推定的 RNA 依赖性 RNA 聚合酶（RdRp），由 826 个氨基酸组成。系统发育分析表明，AnV1 是 Totiviridae 家族 Victorivirus 属的一个新成员。据我们所知，这是首例报道感染黑曲霉的维多利尔病毒的完整基因组序列。
Zotero 插件