一种新型的感染构巢曲霉的真菌病毒，与二分病毒科一新属的病毒密切相关。

A novel mycovirus infecting Aspergillus nidulans that is closely related to viruses in a new genus of the family Partitiviridae.

机构信息

Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education, Guizhou Medical University, Guiyang, 550004, China.

Key Laboratory of Medical Molecular Biology, Guizhou Medical University, Guiyang, 550004, Guizhou Province, China.

出版信息

Arch Virol. 2021 Feb;166(2):659-664. doi: 10.1007/s00705-020-04930-x. Epub 2021 Jan 6.

DOI:10.1007/s00705-020-04930-x

PMID:33404858

Abstract

The bisegmented genome of a novel double-stranded (ds) RNA mycovirus, named "Aspergillus nidulans partitivirus 1" (AnPV1), isolated from the fungus Aspergillus nidulans strain HJ5-47, was sequenced and analyzed. AnPV1 contains two segments, AnPV1-1 and AnPV1-2. AnPV1-1 has 1837 bp with an open reading frame (ORF) that potentially encodes a putative RNA-dependent RNA polymerase (RdRp) of 572 amino acids (aa). AnPV1-2 has 1583 bp with an ORF encoding a putative capsid protein (CP) of 488 aa. Phylogenetic analyses indicated that AnPV1 and related viruses clustered in a group that could represent a new unclassified genus in the family Partitiviridae.

摘要

一株新型双链（ds）RNA 真菌病毒，命名为“aspergillus nidulans partitivirus 1”（AnPV1），从真菌aspergillus nidulans 菌株 HJ5-47 中分离出来，其双节段基因组已被测序和分析。AnPV1 包含两个片段，AnPV1-1 和 AnPV1-2。AnPV1-1 长 1837bp，含有一个潜在编码 572 个氨基酸（aa）的 RNA 依赖的 RNA 聚合酶（RdRp）的开放阅读框（ORF）。AnPV1-2 长 1583bp，含有一个编码 488 个氨基酸的衣壳蛋白（CP）的 ORF。系统发育分析表明，AnPV1 及其相关病毒聚集在一个群体中，该群体可能代表了二分病毒科中的一个新未分类属。