Tareen Bisma, Faith Hayden, Waheed Abdul, Ullah Asad, Kavuri Sravan K
Internal Medicine, Bolan Medical College, Quetta, PAK.
Oncology, Medical College of Georgia-Augusta University, Augusta, USA.
Cureus. 2022 Mar 18;14(3):e23289. doi: 10.7759/cureus.23289. eCollection 2022 Mar.
An inflammatory myofibroblastic tumor (IMT) is an uncommon, benign tumor of myofibroblastic spindle cells. An IMT can occur in any part of the body. However, involving kidney is exceedingly rare. When this rare entity occurs in children, it becomes incredibly challenging to distinguish this rare entity from other malignancies such as Wilms tumor. Although imaging studies of the abdomen and pelvis add to the diagnosis, however, histological examination and immunohistochemical staining remain the gold standard for the precise diagnosis of this rare entity. To the best of our knowledge, only 48 cases of renal IMT have been published in the medical literature so far. We report the case of a nine-month-old girl who was brought with complaints of hematuria, and later, imaging and histological confirmation revealed an anaplastic lymphoma kinase (ALK)-negative IMT of the kidney.
炎性肌成纤维细胞瘤（IMT）是一种罕见的肌成纤维细胞梭形细胞良性肿瘤。IMT可发生于身体的任何部位。然而，累及肾脏极为罕见。当这种罕见情况发生在儿童身上时，将其与其他恶性肿瘤（如肾母细胞瘤）区分开来极具挑战性。尽管腹部和骨盆的影像学检查有助于诊断，但组织学检查和免疫组化染色仍是精确诊断这种罕见疾病的金标准。据我们所知，迄今为止医学文献中仅发表了48例肾IMT病例。我们报告了一例9个月大的女童，她因血尿前来就诊，后来影像学和组织学检查证实为肾脏间变性淋巴瘤激酶（ALK）阴性的IMT。
