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乙型肝炎暴露与急诊医生:风险评估及乙肝疫苗更新

Hepatitis B exposure and the emergency physician: risk assessment and hepatitis vaccine update.

作者信息

Trott A

出版信息

Am J Emerg Med. 1987 Jan;5(1):54-9. doi: 10.1016/0735-6757(87)90291-9.

Abstract

Since the hepatitis B vaccine was licensed in 1981, emergency physicians have had the opportunity to be immunized against the hepatitis B virus (HBV). The factors that affect the decision to undergo vaccination include the risk of acquiring an HBV infection in emergency practice, the prevaccination immune status of emergency physicians who have knowledge of their hepatitis serum marker profile, and the efficacy and safety of the vaccine. Emergency physicians have a significant risk of acquiring an HBV infection and are recommended by the Centers for Disease Control to receive vaccination. However, emergency physicians are often incidentally tested for HBV serum markers before immunization. Recent investigations have shown that seropositivity for hepatitis surface antibody (anti-HBs) does not necessarily preclude the need for immunization. Finally, experience with 750,000 doses has shown that it is a highly effective and extremely safe vaccine.

摘要

自1981年乙肝疫苗获得许可以来,急诊医生有机会接种乙肝病毒(HBV)疫苗。影响接种疫苗决策的因素包括在急诊工作中感染HBV的风险、了解自身肝炎血清标志物情况的急诊医生接种前的免疫状态,以及疫苗的有效性和安全性。急诊医生有感染HBV的重大风险,疾病控制中心建议他们接种疫苗。然而,急诊医生在接种疫苗前常被意外检测HBV血清标志物。最近的调查表明,乙肝表面抗体(抗-HBs)血清阳性不一定排除接种疫苗的必要性。最后,75万剂疫苗的使用经验表明,它是一种高效且极其安全的疫苗。

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