Huang Hsien-Po, Tsai Shang-Feng
Department of Internal Medicine, Taichung Veterans General Hospital, Taichung 40705, Taiwan.
Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung 40227, Taiwan.
Diagnostics (Basel). 2022 Apr 6;12(4):906. doi: 10.3390/diagnostics12040906.
Amyloidoma of the chest wall is an uncommon entity, consisting of a solitary tumor-like deposit of amyloid. Until now, while rarely reported, it was mostly presented with back pain and swelling. Here, we report the first case of a chest wall amyloidoma initially presented with fever of unknown origin. Due to the rarity of the lesion as a primary entity, protein electrophoresis and long-term follow-up are required. In addition, patients undergoing long-term hemodialysis are particularly at risk for such acquired amyloidosis. However, soft-tissue tumors, considered as amyloidoma, is also rare in patients with long-term hemodialysis. For patients with a fever of unknown primary origin, clinicians should keep amyloidoma in mind, especially in high-risk populations.
胸壁淀粉样瘤是一种罕见的疾病，由淀粉样蛋白的单个肿瘤样沉积物组成。到目前为止，虽然报道很少，但大多表现为背痛和肿胀。在此，我们报告首例最初表现为不明原因发热的胸壁淀粉样瘤病例。由于该病变作为原发性疾病较为罕见，因此需要进行蛋白电泳和长期随访。此外，长期接受血液透析的患者尤其有发生这种获得性淀粉样变性的风险。然而，在长期血液透析患者中，被认为是淀粉样瘤的软组织肿瘤也很罕见。对于不明原因发热的患者，临床医生应考虑到淀粉样瘤，尤其是在高危人群中。
