Tasic Nebojsa, Tasic Danijela, Kovacevic Zorana, Filipovic Marko, Arsic Milan, Bozovic-Ogarevic Sladjana, Despotovic Biljana, Bojic Milovan, Maksimovic Zlatko, Zdravkovic Nebojsa, Mijailovic Sara, Zivkovic Vladimir, Nikolic Turnic Tamara, Jakovljevic Vladimir
Institute for Cardiovascular Diseases Dedinje, 5 Heroja Milana Tepica Street, 11000 Belgrade, Serbia.
General Health Center "Sveti Vračevi", 53 Srpske Vojske Street, 76300 Bijeljina, Bosnia and Herzegovina.
Diagnostics (Basel). 2022 Apr 6;12(4):914. doi: 10.3390/diagnostics12040914.
Background: The purpose of this study was to compare home and office BP in the adjustment of antihypertensive treatment. Methods: This study was an open, prospective, noninterventional, multicenter clinical trial that occurred between July 2019 and February 2020, in 34 cities in the territory of the Republic of Serbia, which monitored 1581 participants for 6 months. Depending on the used blood pressure monitoring method used, all patients were divided into control (office BP monitoring) and experimental (home BP telemonitoring) groups. We collected anamnestic data and data about systolic blood pressure (SP), in mmHg, diastolic blood pressure (DP), in mmHg, and heart rate (HR), in beats/minute, from all patients. Results: SP values were significantly different at baseline, and at the second, third, and fourth visits between the two tested groups. Home and office BP decreased significantly (p < 0.000) during the 6-month follow-up. We observed a statistically significant influence of the presence of diabetes mellitus and dyslipidemia on the dynamics of differences between SP monitoring values. Conclusions: Our study suggests that novel technologies in BP monitoring can be excellent alternatives for BP assessment in hypertensive patients with other cardiovascular risk factors such as diabetes and dyslipidemia.
本研究的目的是比较家庭血压和诊室血压在调整降压治疗中的情况。方法:本研究是一项开放、前瞻性、非干预性、多中心临床试验,于2019年7月至2020年2月在塞尔维亚共和国境内的34个城市进行,对1581名参与者进行了6个月的监测。根据所使用的血压监测方法,所有患者被分为对照组(诊室血压监测)和试验组(家庭血压远程监测)。我们收集了所有患者的既往史数据以及收缩压(SP,单位为mmHg)、舒张压(DP,单位为mmHg)和心率(HR,单位为次/分钟)的数据。结果:在基线以及两次测试组之间的第二次、第三次和第四次访视时,SP值存在显著差异。在6个月的随访期间,家庭血压和诊室血压均显著下降(p < 0.000)。我们观察到糖尿病和血脂异常的存在对SP监测值之间差异的动态变化有统计学显著影响。结论:我们的研究表明,血压监测中的新技术对于患有糖尿病和血脂异常等其他心血管危险因素的高血压患者的血压评估而言,可能是极佳的替代方法。