Department of Periodontics, School of Dentistry, University of Granada, 18071 Granada, Spain.
Gastroenterology Service, Virgen de la Arrixaca University Hospital, 30120 Murcia, Spain.
Medicina (Kaunas). 2022 Apr 15;58(4):546. doi: 10.3390/medicina58040546.
There is very recent and strong evidence relating to colorectal cancer. In this narrative review, we update the knowledge about gingival dysbiosis and the characteristics of as one of the main bacteria related to periodontitis. We provide data on microbiome, epidemiology, risk factors, prognosis, and treatment of colorectal cancer, one of the most frequent tumours diagnosed and whose incidence increases every year. We describe, from its recent origin, the relationship between this bacterium and this type of cancer and the knowledge and emerging mechanisms that scientific evidence reveals in an updated way. A diagram provided synthesizes the pathogenic mechanisms of this relationship in a comprehensive manner. Finally, the main questions and further research perspectives are presented.
有非常新的和强有力的证据与结直肠癌有关。在这篇叙述性综述中，我们更新了关于牙龈失调的知识，并介绍了 作为与牙周炎有关的主要细菌之一的特征。我们提供了关于结直肠癌的微生物组、流行病学、危险因素、预后和治疗的数据，结直肠癌是最常见的诊断肿瘤之一，其发病率每年都在增加。我们从其最近的起源描述了这种细菌与这种类型癌症之间的关系，以及科学证据以更新的方式揭示的知识和新兴机制。提供的图表全面综合了这种关系的致病机制。最后，提出了主要问题和进一步的研究展望。
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