精准医学时代的癌症演变
Cancer Evolution in Precision Medicine Era.
作者信息
Karagiannis Dimitris, Rampias Theodoros
机构信息
Department of Genetics and Development, Columbia University Medical Center, New York, NY 10032, USA.
Biomedical Research Foundation of the Academy of Athens, 11527 Athens, Greece.
出版信息
Cancers (Basel). 2022 Apr 8;14(8):1885. doi: 10.3390/cancers14081885.
Abstract
Recent advances in our understanding of cancer, driven mainly by the emergence of new technologies have highlighted that heterogeneity shapes not only the genetic profile of tumors but also their epigenetic and gene expression profile [...].
摘要
主要由新技术的出现推动的我们对癌症理解的最新进展突出表明，异质性不仅塑造了肿瘤的基因特征，也塑造了它们的表观遗传和基因表达特征[...]。
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