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自身免疫性脱髓鞘疾病的磁共振成像:放射科医生面临的诊断挑战——两例报告及文献综述

Magnetic Resonance Imaging of Autoimmune Demyelinating Diseases as a Diagnostic Challenge for Radiologists: Report of Two Cases and Literature Review.

作者信息

Pierro Antonio, Posa Alessandro, Addona Tiziana, Petrosino Antonella, Galasso Vittorio, Tanzilli Alessandro, Niro Sara, Simone Fernando Antonio, Cilla Savino, Iezzi Roberto

机构信息

Dipartimento di Radiologia, Ospedale Regionale, "A. Cardarelli", ASReM, Contrada Tappino, 86100 Campobasso, Italy.

Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, U.O.C. Radiologia Diagnostica e Interventistica Generale, Fondazione Policlinico Universitario, "A. Gemelli"-IRCCS, L.go A. Gemelli 8, 00168 Rome, Italy.

出版信息

Life (Basel). 2022 Mar 28;12(4):488. doi: 10.3390/life12040488.

DOI:10.3390/life12040488
PMID:35454978
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9027326/
Abstract

The magnetic resonance characteristics of autoimmune demyelinating diseases are complex and represent a challenge for the radiologist. In this study we presented two different cases of detected autoimmune demyelinating diseases: one case of acute disseminated encephalomyelitis and one case of neuromyelitis optica, respectively. Expected and unexpected findings of magnetic resonance imaging examination for autoimmune demyelinating diseases were reported in order to provide a valuable approach for diagnosis. In particular, we highlight, review and discuss the presence of several uncommon imaging findings which could lead to a misinterpretation. The integration of magnetic resonance imaging findings with clinical and laboratory data is necessary to provide a valuable diagnosis.

摘要

自身免疫性脱髓鞘疾病的磁共振特征复杂,对放射科医生来说是一项挑战。在本研究中,我们展示了两例检测出的自身免疫性脱髓鞘疾病:分别为一例急性播散性脑脊髓炎和一例视神经脊髓炎。报告了自身免疫性脱髓鞘疾病磁共振成像检查的预期和意外发现,以便提供有价值的诊断方法。特别是,我们着重强调、回顾并讨论了几种可能导致误诊的罕见影像学表现。将磁共振成像结果与临床和实验室数据相结合对于做出有价值的诊断是必要的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/178f/9027326/fdf6a3aed118/life-12-00488-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/178f/9027326/a75c86a30ee1/life-12-00488-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/178f/9027326/cc0629ec0fae/life-12-00488-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/178f/9027326/2c1de7e8f8df/life-12-00488-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/178f/9027326/54cdf1cba900/life-12-00488-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/178f/9027326/fdf6a3aed118/life-12-00488-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/178f/9027326/a75c86a30ee1/life-12-00488-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/178f/9027326/cc0629ec0fae/life-12-00488-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/178f/9027326/2c1de7e8f8df/life-12-00488-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/178f/9027326/54cdf1cba900/life-12-00488-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/178f/9027326/fdf6a3aed118/life-12-00488-g005.jpg

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Diagnostic approach in multiple sclerosis with MRI: an update.MRI 诊断多发性硬化症:最新进展。
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Mult Scler Relat Disord. 2020 Jan;37:101452. doi: 10.1016/j.msard.2019.101452. Epub 2019 Oct 15.
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Diagnostic Approach to Intrinsic Abnormality of Spinal Cord Signal Intensity.脊髓信号强度固有异常的诊断方法。
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Neuromyelitis Optica Spectrum Disorder and Anti-MOG Syndromes.视神经脊髓炎谱系障碍和抗髓鞘少突胶质细胞糖蛋白综合征
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Multiple Sclerosis: Diagnosis and Differential Diagnosis.多发性硬化症:诊断与鉴别诊断
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