Alam Shamsul, Ferini Gianluca, Muhammad Nur, Ahmed Nazmin, Wakil Abu Naim Mohammad, Islam Kazi Mohammad Atiqul, Arifin Mohammad Samsul, Al Mahbub Abdullah, Habib Riad, Mojumder Mosiur Rahman, Vats Atul, Chaurasia Bipin
Department of Neurosurgery, Bangabandhu Sheikh Mujib Medical University, Dhaka 1000, Bangladesh.
Department of Radiation Oncology, REM Radioterapia SRL, Viagrande, 95029 Catania, Italy.
Life (Basel). 2022 Mar 28;12(4):492. doi: 10.3390/life12040492.
(1) Background: The aim of the present study was to evaluate our institutional outcome in tuberculum sellae meningioma (TSM) patients treated microsurgically using multiple skull base approaches, including a transcranial approach and an extended endonasal transsphenoidal approach. (2) Materials and Methods: This is a retrospective study that includes 34 patients with TSM. The study aimed to observe the efficacy of the different common approaches used by a single neurosurgeon. All the patients were evaluated preoperatively and during follow-up with campimetry, head CT scan, and post-contrast MRI. (3) Results: After a transcranial approach, visual acuity improved in 86.20%, was stable in 10.34%, and deteriorated in 3.45%. Through transsphenoidal surgery, vision improved in 80%, was static in 20%, and deteriorated in 0%. Transcranial approaches included pterional, mini-bifrontal basal, and supraciliary keyhole microscopic craniotomies. Gross total removal was performed in 58.82%, near total in 10.34%, and partial removal in 3.45%. The transcranial/supraciliary keyhole endoscopic-assisted approach showed a gross total removal rate of 80%, and near total in 20%. The transsphenoidal approach showed a gross total removal rate of 60%, near total in 20%, and partial removal in 20%. (4) Conclusion: Endoscopic-assisted keyhole supraciliary mini craniotomy for resection of tuberculum sellae meningioma offers low morbidity and good visual outcome. The endonasal route is preferred for the removal of TSM when they are small and midline placed. The major limitation of this approach is a narrow surgical corridor and the restriction on midline-placed lesions. Gross total removal was better achieved with mini-bifrontal basal and pterional craniotomies.
(1) 背景:本研究的目的是评估我院采用多种颅底入路(包括经颅入路和扩大经鼻蝶窦入路)显微手术治疗鞍结节脑膜瘤(TSM)患者的疗效。(2) 材料与方法:这是一项回顾性研究,纳入了34例TSM患者。该研究旨在观察由单一神经外科医生使用的不同常用入路的疗效。所有患者在术前及随访期间均接受视野计检查、头部CT扫描和增强MRI检查。(3) 结果:经颅入路后,视力改善者占86.20%,稳定者占10.34%,恶化者占3.45%。经蝶窦手术中,视力改善者占80%,稳定者占20%,恶化者占0%。经颅入路包括翼点入路、额下基底双额入路和眉弓锁孔显微镜下开颅术。全切率为58.82%,次全切除率为10.34%,部分切除率为3.45%。经颅/眉弓锁孔内镜辅助入路的全切率为80%,次全切除率为20%。经蝶窦入路的全切率为60%,次全切除率为20%,部分切除率为20%。(4) 结论:内镜辅助眉弓锁孔微创开颅术切除鞍结节脑膜瘤具有低发病率和良好的视力预后。当TSM较小且位于中线时,经鼻入路是首选的切除方法。该入路的主要局限性是手术通道狭窄以及对中线部位病变的限制。额下基底双额开颅术和翼点开颅术能更好地实现全切。