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罗马尼亚COVID-19疫苗接种犹豫情况:全国性横断面研究

COVID-19 Parental Vaccine Hesitancy in Romania: Nationwide Cross-Sectional Study.

作者信息

Manolescu Loredana Sabina Cornelia, Zaharia Corneliu Nicolae, Dumitrescu Anca Irina, Prasacu Irina, Radu Mihaela Corina, Boeru Adrian Calin, Boidache Liliana, Nita Irina, Necsulescu Andrei, Medar Cosmin, Cristache Corina Marilena, Chivu Razvan Daniel

机构信息

Department of Microbiology, Parasitology and Virology, Faculty of Midwifery and Nursing, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.

Department of Virology, Institute of Virology "Stefan S. Nicolau", 030304 Bucharest, Romania.

出版信息

Vaccines (Basel). 2022 Mar 23;10(4):493. doi: 10.3390/vaccines10040493.

DOI:10.3390/vaccines10040493
PMID:35455243
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9024952/
Abstract

BACKGROUND

COVID-19 vaccination started in Romania in December 2020. Child vaccination started in 2021 with children aged 12-15 years in August. For children aged 5-11 years, vaccination started in January 2022. The aim of our study was to describe COVID-19 vaccination hesitancy in Romanian children and vaccine acceptability in the general population. As parental consent is required for child vaccination in Romania, these aspects have a significant association.

METHODS

An analytical cross-sectional survey was conducted in October and November 2021 during the peak of the 4th COVID-19 wave.

RESULTS

After validation, 1645 participants formed the main study group: median age 35 years, 72.83% women, and 35.44% from the medical domain. In total, 1311 (79.70%) participants were vaccinated against COVID-19 and 188 (11.42%) had vaccinated their 12-18-year-old children against COVID-19. Parents' level of education, geographic area of residence, and COVID-19 vaccination status were significantly associated with COVID-19 vaccination. The hesitancy factors of child vaccination included the novelty of COVID-19 vaccines (62, 47.32%), fear of adverse reactions (32, 24.42%), and anti-vaccinism in general (29, 22.13%). In the studied group, only 188 (11.42%) participants recommended vaccination of 5-11-year-old children. Vaccine acceptability was higher in the general population (1311, 79.70%) than in the medical domain (326 out of 583, 55.91%). General vaccine hesitancy was based mainly on beliefs regarding inefficiency (131, 39.22%) and fears about the side effects of the vaccine (76, 22.75%).

CONCLUSIONS

Overall, the acceptability of COVD-19 vaccines in the Romanian population was influenced by the level of education, area of residence, and being a COVID-19-vaccinated parent. Public health intervention programs are essential.

摘要

背景

罗马尼亚于2020年12月开始新冠疫苗接种。儿童接种于2021年开始,8月为12至15岁儿童接种。对于5至11岁儿童,接种于2022年1月开始。我们研究的目的是描述罗马尼亚儿童对新冠疫苗接种的犹豫态度以及普通人群对疫苗的接受程度。由于罗马尼亚儿童接种疫苗需要家长同意,这些方面存在显著关联。

方法

于2021年10月和11月在第四波新冠疫情高峰期进行了一项分析性横断面调查。

结果

经过验证,1645名参与者组成了主要研究组:中位年龄35岁,女性占72.83%,35.44%来自医疗领域。总共有1311名(79.70%)参与者接种了新冠疫苗,188名(11.42%)为其12至18岁的孩子接种了新冠疫苗。家长的教育水平、居住地理区域和新冠疫苗接种状况与新冠疫苗接种显著相关。儿童接种疫苗的犹豫因素包括新冠疫苗的新颖性(62人,47.32%)、对不良反应的恐惧(32人,24.42%)以及总体上的反疫苗主义(29人,22.13%)。在研究组中,只有188名(11.42%)参与者建议为5至11岁儿童接种疫苗。普通人群中疫苗的接受度(1311人,79.70%)高于医疗领域(583人中的326人,55.91%)。总体疫苗犹豫主要基于对疫苗无效性的信念(131人,39.22%)以及对疫苗副作用的恐惧(76人,22.75%)。

结论

总体而言,罗马尼亚人群对新冠疫苗的接受度受教育水平、居住地区以及是否为接种新冠疫苗的家长影响。公共卫生干预项目至关重要。