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16岁以下儿童新冠疫苗接种的家长犹豫情况:一项针对工厂工人的横断面混合方法研究

Parental hesitancy on COVID-19 vaccination of children under the age of 16: A cross-sectional mixed-methods study among factory workers.

作者信息

Aung Kyaw Thiha, Htun Ye Minn, Htet Zin Lin, Soe Yan Naing Myint, Ko Phyo Ko, Oo Win, Aung May Soe, Win Tun Tun

机构信息

Department of Prevention and Research Development of Hepatitis, AIDS and Other Viral Diseases, Health and Disease Control Unit, Nay Pyi Taw, Myanmar.

Department of Preventive and Social Medicine, Defence Services Medical Academy, Yangon, Myanmar.

出版信息

PLoS One. 2025 Jun 26;20(6):e0327056. doi: 10.1371/journal.pone.0327056. eCollection 2025.

Abstract

BACKGROUND

Thanks to the development of COVID-19 vaccines, now they can be safely and effectively used to guard COVID-19 patients against severe illness, hospitalization, and even mortality. However, parents' unwillingness to vaccinate their children depends on a large extent on factors beyond the availability of vaccines, and understanding the factors associated with parental vaccine hesitancy has become increasingly important to the development of the COVID-19 vaccine program. Therefore, this study aimed to determine the parental COVID-19 vaccine hesitancy to their children and its associated factors among factory workers in Myanmar.

METHODS

A cross-sectional mixed-methods study was conducted as an explanatory sequential design, at Tri Star tyre factory (Ywar Ma), Yangon, Myanmar from August 2022 to February 2023. A total of 170 factory workers with children under the age of 16 participated in this study. The quantitative data were collected by the face-to-face interviews using a pretested structured questionnaire that included the Oxford COVID-19 vaccine hesitancy scale. Data were analyzed by using binary logistic regression to identify associated factors of parental hesitancy. Adjusted odds ratio (AOR) with a 95% confidence interval (CI) was computed to determine the level of significance with a p value ≤ 0.05. A subsample of 6 participants from each "hesitant group" and "non-hesitant group" towards COVID-19 vaccination was interviewed by the individual in-depth-interview guide to provide the reasons for their willingness or unwillingness to vaccinate to their children. The thematic analysis was undertaken for the qualitative data.

RESULTS

Among the total, 18.2% (95% CI: 12.7-24.9%) of the parents were hesitant to vaccinate their children against COVID-19 while 25.9% (95% CI: 19.5-33.1%) responded as unsure and 55.9% (95% CI: 48.1-63.5%) were non-hesitant for vaccination to their children. Male (AOR: 3.04, 95% CI: 1.35-6.84) and those who were not infected with SARS-CoV-2 (AOR: 2.66, 95% CI: 1.06-6.70) were significantly associated with parental COVID-19 vaccine hesitancy. The most common reasons for the unwillingness to receive the COVID-19 vaccination to their children were too young for vaccination, concerns about the safety of the vaccines, uncertainty about the effectiveness of the vaccines, and lack of trust in the origin of the vaccines.

CONCLUSIONS

In this study, nearly one-fifth of the parents were hesitant to vaccinate their children against COVID-19. The findings of this study suggested that the government and healthcare professionals should provide health education about the importance of COVID-19 vaccination and the safety and efficacy of currently providing COVID-19 vaccines using mainstream media to improve the proportion of children getting vaccinated against COVID-19.

摘要

背景

得益于新冠疫苗的研发,如今它们能够安全有效地用于保护新冠患者免受重症、住院甚至死亡的威胁。然而,家长不愿为孩子接种疫苗在很大程度上取决于疫苗可及性之外的因素,了解与家长疫苗犹豫相关的因素对新冠疫苗接种计划的开展愈发重要。因此,本研究旨在确定缅甸工厂工人对其子女接种新冠疫苗的犹豫情况及其相关因素。

方法

于2022年8月至2023年2月在缅甸仰光的三星轮胎厂(Ywar Ma)开展了一项横断面混合方法研究,采用解释性序列设计。共有170名有16岁以下子女的工厂工人参与了本研究。通过面对面访谈,使用经过预测试的结构化问卷收集定量数据,该问卷包括牛津新冠疫苗犹豫量表。采用二元逻辑回归分析数据以确定家长犹豫的相关因素。计算调整后的优势比(AOR)及95%置信区间(CI),以p值≤0.05确定显著性水平。对每个新冠疫苗接种“犹豫组”和“非犹豫组”的6名参与者进行个体深入访谈,以了解他们愿意或不愿意为子女接种疫苗的原因。对定性数据进行主题分析。

结果

总体而言,18.2%(95%CI:12.7 - 24.9%)的家长对为子女接种新冠疫苗犹豫不决,25.9%(95%CI:19.5 - 33.1%)表示不确定,55.9%(95%CI:48.1 - 63.5%)不犹豫为子女接种疫苗。男性(AOR:3.04,95%CI:1.35 - 6.84)以及未感染严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的人(AOR:2.66,95%CI:1.06 - 6.70)与家长对新冠疫苗的犹豫显著相关。不愿为子女接种新冠疫苗的最常见原因是孩子太小不能接种、担心疫苗安全性、对疫苗有效性不确定以及对疫苗来源缺乏信任。

结论

在本研究中,近五分之一的家长对为子女接种新冠疫苗犹豫不决。本研究结果表明,政府和医护人员应利用主流媒体提供有关新冠疫苗接种重要性以及当前所提供新冠疫苗安全性和有效性的健康教育,以提高儿童接种新冠疫苗的比例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adbe/12200862/c255ca93499e/pone.0327056.g001.jpg

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