Daojorn Rangsan, Suwannaprom Puckwipa, Suttajit Siritree, Kanjanarat Penkarn, Tiengket Prangtong, Lallemant Marc
Health and Medicine Policy Center (HMPC), Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50000, Thailand.
Omkoi Hospital, Chiang Mai 50310, Thailand.
Children (Basel). 2022 Apr 13;9(4):552. doi: 10.3390/children9040552.
Lack of access to child-appropriate medicines results in off-label use. This study aimed to explore medicine management for paediatric patients and to highlight the challenges of the healthcare system under the universal health coverage of Thailand. Semi-structured interviews were conducted with 35 healthcare practitioners working in the public hospital network of Chiang Mai province from February to September 2020. Participants were asked about their experiences in managing the medicine supply for children. Findings revealed that paediatric patients had limited access to age-appropriate medicines. Children's medicines are rarely selected for inclusion into hospital formularies because of constraining regulations and limited budgets. Additionally, child-appropriate formulations are unavailable on the market. Pharmaceutical compounding is unavoidable. Prepared products are provided weekly or monthly because of product stability concerns. Often, tablets are dispensed, and caregivers are instructed to cut up a tablet and disperse it in syrup in order to obtain a smaller dose in a dosage form appropriate for children to use at home. Without systematic support, access to safe and quality medicines for children is limited.
无法获取适合儿童的药品导致了药品的超说明书使用。本研究旨在探索儿科患者的药品管理,并凸显泰国全民健康覆盖下医疗系统所面临的挑战。2020年2月至9月,对清迈省公立医院网络中的35名医疗从业者进行了半结构化访谈。参与者被问及他们在管理儿童药品供应方面的经验。研究结果显示,儿科患者获取适合其年龄药品的机会有限。由于规定限制和预算有限,儿童用药很少被选入医院药品目录。此外,市场上没有适合儿童的剂型。药物配制不可避免。出于对产品稳定性的担忧,配制好的药品每周或每月提供一次。通常发放的是片剂,会指导护理人员将片剂切开并分散在糖浆中,以便在家中获得适合儿童使用的较小剂量剂型。如果没有系统的支持,儿童获取安全和优质药品的机会将受到限制。