Vera-Urbina Fernando, Dos Santos-Torres María F, Godoy-Vitorino Filipa, Torres-Hernández Bianca A
Faculty of Natural Sciences, University of Puerto Rico at Rio Piedras, San Juan 00925, Puerto Rico.
Department of Microbiology, School of Medicine, Medical Sciences Campus, University of Puerto Rico, San Juan 00925, Puerto Rico.
Microorganisms. 2022 Mar 31;10(4):763. doi: 10.3390/microorganisms10040763.
The gut-brain axis is the biological connection between the enteric and the central nervous systems. Given the expansion of the microbial sciences with the new human microbiome field facilitated by the decrease in sequencing costs, we now know more about the role of gut microbiota in human health. In this short review, particular focus is given to the gut-brain axis and its role in psychiatric diseases such as anxiety and depression. Additionally, factors that contribute to changes in the gut-brain axis, including the gut microbiome, nutrition, the host's genome, and ethnic difference, are highlighted. Emphasis is given to the lack of studies on Hispanic populations, despite the fact this ethnic group has a higher prevalence of anxiety and depression in the US.
肠-脑轴是肠道和中枢神经系统之间的生物学联系。随着测序成本的降低，微生物科学在新的人类微生物组领域不断扩展，我们现在对肠道微生物群在人类健康中的作用有了更多了解。在这篇简短的综述中，我们特别关注肠-脑轴及其在焦虑和抑郁等精神疾病中的作用。此外，还强调了导致肠-脑轴变化的因素，包括肠道微生物组、营养、宿主基因组和种族差异。尽管西班牙裔人群在美国焦虑和抑郁的患病率较高，但目前针对该人群的研究却很匮乏，这一点也得到了强调。
