氰尿酸及其氯化衍生物的毒理学研究综述。
A review of toxicology studies on cyanurate and its chlorinated derivatives.
作者信息
Hammond B G, Barbee S J, Inoue T, Ishida N, Levinskas G J, Stevens M W, Wheeler A G, Cascieri T
出版信息
Environ Health Perspect. 1986 Nov;69:287-92. doi: 10.1289/ehp.8669287.
Abstract
Chlorinated cyanurates are added to swimming pools as disinfectants. In the presence of water, these materials hydrolyze to yield cyanurate and hypochlorous acid. To evaluate the safety of exposure to these materials, a comprehensive testing program was undertaken. This review summarizes the results of acute and subchronic tests on chlorinated isocyanurates. Findings from acute, subchronic, reproduction, metabolism, mutagenicity, and chronic/carcinogenicity tests on cyanurate are also summarized. Results from these tests indicate that chlorinated isocyanurates are safe for use in swimming pools.
摘要
氯代氰尿酸盐作为消毒剂添加到游泳池中。在有水存在的情况下，这些物质会水解生成氰尿酸和次氯酸。为评估接触这些物质的安全性，开展了一项全面的测试项目。本综述总结了氯代异氰尿酸盐的急性和亚慢性测试结果。还总结了氰尿酸的急性、亚慢性、生殖、代谢、致突变性以及慢性/致癌性测试的结果。这些测试结果表明，氯代异氰尿酸盐用于游泳池是安全的。
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