Suppr超能文献

分析 COVID-19 出院患者认知障碍、营养指标与临床病程的关系——初步报告。

Analysis of the Relationship among Cognitive Impairment, Nutritional Indexes and the Clinical Course among COVID-19 Patients Discharged from Hospital-Preliminary Report.

机构信息

Department of Anesthesiology and Intensive Care, COVID-19 ICU, Military Institute of Medicine, 04-141 Warsaw, Poland.

Faculty of Psychology, University of Economics and Human Sciences in Warsaw, 01-043 Warsaw, Poland.

出版信息

Nutrients. 2022 Apr 11;14(8):1580. doi: 10.3390/nu14081580.

Abstract

Numerous data indicate the presence of cognitive impairment in people who have undergone COVID-19, often called COVID Fog (CF). This phenomenon persists even 6 months after infection, and its etiology and pathogenesis are not fully known. The aim of this article was to analyze the relationship among cognitive functioning, clinical data and nutrition indexes in patients discharged from the COVID-19 hospital of the Military Institute of Medicine, Warsaw, Poland. The sample comprised 17 individuals-10 women and 7 men, with ages of 65 ± 14 years. Cognitive impairment was measured with the use of the Montreal Cognitive Assessment (MoCA). The nutrition parameters included: hemoglobin, red blood cells, total cholesterol and its fractions, triglycerides, total protein, albumin, urea, creatinine, phosphates, calcium and sodium. The analysis showed that albumin concentration significantly correlated with the total MoCA score and especially with the short-term memory test score. Conversely, total cholesterol, and especially LDL concentrations, were highly and negatively associated with the MoCA score. In conclusion: markers of nutritional status are correlated with the severity of CF. Individuals with malnutrition or risk of malnutrition should be screened for CF. Further studies need to be performed in this area.

摘要

大量数据表明,COVID-19 患者存在认知障碍,通常称为 COVID 雾(CF)。这种现象在感染后甚至持续 6 个月,其病因和发病机制尚未完全清楚。本文旨在分析波兰华沙军事医学研究所 COVID-19 医院出院患者的认知功能、临床数据和营养指标之间的关系。样本包括 17 人,其中 10 名女性,7 名男性,年龄 65 ± 14 岁。认知障碍采用蒙特利尔认知评估(MoCA)进行测量。营养参数包括:血红蛋白、红细胞、总胆固醇及其各组分、甘油三酯、总蛋白、白蛋白、尿素、肌酐、磷酸盐、钙和钠。分析表明,白蛋白浓度与 MoCA 总分显著相关,特别是与短期记忆测试得分相关。相反,总胆固醇,尤其是 LDL 浓度,与 MoCA 评分高度负相关。结论:营养状况标志物与 CF 的严重程度相关。应筛查营养不良或存在营养不良风险的个体是否存在 CF。需要在该领域开展进一步的研究。

相似文献

6
[Clinical study on the factors associated with long-term cognitive function in patients with sepsis].[脓毒症患者长期认知功能相关因素的临床研究]
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2019 May;31(5):614-618. doi: 10.3760/cma.j.issn.2095-4352.2019.05.018.

本文引用的文献

3
Management of disease-related malnutrition for patients being treated in hospital.医院治疗患者疾病相关营养不良的管理。
Lancet. 2021 Nov 20;398(10314):1927-1938. doi: 10.1016/S0140-6736(21)01451-3. Epub 2021 Oct 14.
4
Qualitative smell/taste disorders as sequelae of acute COVID-19.急性 COVID-19 后遗症中的嗅觉/味觉定性障碍。
Neurol Sci. 2021 Dec;42(12):4921-4926. doi: 10.1007/s10072-021-05611-6. Epub 2021 Sep 23.
9
Attributes and predictors of long COVID.长新冠的特征和预测因素。
Nat Med. 2021 Apr;27(4):626-631. doi: 10.1038/s41591-021-01292-y. Epub 2021 Mar 10.
10
Long-Lasting Cognitive Abnormalities after COVID-19.新冠病毒感染后的长期认知异常
Brain Sci. 2021 Feb 13;11(2):235. doi: 10.3390/brainsci11020235.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验