• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

电机神经冲动遥感系统。

Remote Sensing System for Motor Nerve Impulse.

机构信息

IMT Bucharest, 77190 Bucharest, Romania.

ICIA, Ctr New Elect Architectures, 050711 Bucharest, Romania.

出版信息

Sensors (Basel). 2022 Apr 7;22(8):2823. doi: 10.3390/s22082823.

DOI:10.3390/s22082823
PMID:35458809
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9027399/
Abstract

In this article, we present our research achievements regarding the development of a remote sensing system for motor pulse acquisition, as a first step towards a complete neuroprosthetic arm. We present the fabrication process of an implantable electrode for nerve impulse acquisition, together with an innovative wirelessly controlled system. In our study, these were combined into an implantable device for attachment to peripheral nerves. Mechanical and biocompatibility tests were performed, as well as in vivo testing on pigs using the developed system. This testing and the experimental results are presented in a comprehensive manner, demonstrating that the system is capable of accomplishing the requirements of its designed application. Most significantly, neural electrical signals were acquired and transmitted out of the body during animal experiments, which were conducted according to ethical regulations in the field.

摘要

本文介绍了我们在开发用于电机脉冲采集的遥感系统方面的研究成果,这是开发完整神经义肢的第一步。我们介绍了用于神经冲动采集的可植入电极的制造过程,以及一种创新的无线控制。在我们的研究中,这些被组合成一种可植入的设备,用于附着在外周神经上。进行了机械和生物相容性测试,并在猪身上使用所开发的系统进行了体内测试。本文全面介绍了这些测试和实验结果,表明该系统能够满足其设计应用的要求。最重要的是,在根据该领域的伦理规定进行的动物实验中,成功获取并传输了神经电信号。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/6ee80a665c51/sensors-22-02823-g024.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/f71652da05aa/sensors-22-02823-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/14f1a0978b95/sensors-22-02823-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/b6eea6f7ad28/sensors-22-02823-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/23e92071d710/sensors-22-02823-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/b89c4b007410/sensors-22-02823-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/c61d2414d64a/sensors-22-02823-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/56b471b6e3db/sensors-22-02823-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/cb60b63c96e9/sensors-22-02823-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/748eba8e451d/sensors-22-02823-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/13460443f7f1/sensors-22-02823-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/3420d28b5795/sensors-22-02823-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/db9f75f2e17c/sensors-22-02823-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/bb787867d004/sensors-22-02823-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/dc6a16e4a782/sensors-22-02823-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/537f15364180/sensors-22-02823-g015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/44781fe7fec5/sensors-22-02823-g016.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/cb90bc886ea9/sensors-22-02823-g017.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/8c4d1e1273e8/sensors-22-02823-g018.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/94535d4cf7da/sensors-22-02823-g019.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/2fde33364e91/sensors-22-02823-g020.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/11716b4da3e9/sensors-22-02823-g021.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/4781fd5b3da4/sensors-22-02823-g022.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/b0c54af41b40/sensors-22-02823-g023.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/6ee80a665c51/sensors-22-02823-g024.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/f71652da05aa/sensors-22-02823-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/14f1a0978b95/sensors-22-02823-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/b6eea6f7ad28/sensors-22-02823-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/23e92071d710/sensors-22-02823-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/b89c4b007410/sensors-22-02823-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/c61d2414d64a/sensors-22-02823-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/56b471b6e3db/sensors-22-02823-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/cb60b63c96e9/sensors-22-02823-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/748eba8e451d/sensors-22-02823-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/13460443f7f1/sensors-22-02823-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/3420d28b5795/sensors-22-02823-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/db9f75f2e17c/sensors-22-02823-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/bb787867d004/sensors-22-02823-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/dc6a16e4a782/sensors-22-02823-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/537f15364180/sensors-22-02823-g015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/44781fe7fec5/sensors-22-02823-g016.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/cb90bc886ea9/sensors-22-02823-g017.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/8c4d1e1273e8/sensors-22-02823-g018.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/94535d4cf7da/sensors-22-02823-g019.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/2fde33364e91/sensors-22-02823-g020.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/11716b4da3e9/sensors-22-02823-g021.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/4781fd5b3da4/sensors-22-02823-g022.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/b0c54af41b40/sensors-22-02823-g023.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a94b/9027399/6ee80a665c51/sensors-22-02823-g024.jpg

相似文献

1
Remote Sensing System for Motor Nerve Impulse.电机神经冲动遥感系统。
Sensors (Basel). 2022 Apr 7;22(8):2823. doi: 10.3390/s22082823.
2
Rodent model for assessing the long term safety and performance of peripheral nerve recording electrodes.用于评估外周神经记录电极长期安全性和性能的啮齿动物模型。
J Neural Eng. 2017 Feb;14(1):016008. doi: 10.1088/1741-2552/14/1/016008. Epub 2016 Dec 9.
3
Interfaces with the peripheral nerve for the control of neuroprostheses.用于神经假肢控制的外周神经接口。
Int Rev Neurobiol. 2013;109:63-83. doi: 10.1016/B978-0-12-420045-6.00002-X.
4
Printable microscale interfaces for long-term peripheral nerve mapping and precision control.用于长期外周神经映射和精确控制的可打印微尺度界面。
Nat Commun. 2020 Aug 21;11(1):4191. doi: 10.1038/s41467-020-18032-4.
5
[Perspectives of effect on new electrode technology with implantable motor prostheses for stimulating peripheral nerves].[植入式运动假体刺激周围神经的新电极技术的效果展望]
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 1999 Dec;16(4):506-10, 515.
6
Selective stimulation of pig radial nerve: comparison of 12-polar and 18-polar cuff electrodes.
Biomed Tech (Berl). 2002;47 Suppl 1 Pt 2:696-9. doi: 10.1515/bmte.2002.47.s1b.696.
7
Optimizing the design of bipolar nerve cuff electrodes for improved recording of peripheral nerve activity.优化双极神经袖套电极设计以改善外周神经活动记录
J Neural Eng. 2017 Jun;14(3):036015. doi: 10.1088/1741-2552/aa6407. Epub 2017 Mar 2.
8
Stimulation selectivity of the “thin-film longitudinal intrafascicular electrode” (tfLIFE) and the “transverse intrafascicular multi-channel electrode” (TIME) in the large nerve animal model.大动物模型中“薄膜纵向神经内电极”(tfLIFE)和“横向神经内多通道电极”(TIME)的刺激选择性。
IEEE Trans Neural Syst Rehabil Eng. 2014 Mar;22(2):400-10. doi: 10.1109/TNSRE.2013.2267936.
9
A micro-scale printable nanoclip for electrical stimulation and recording in small nerves.一种用于小神经电刺激和记录的微型可打印纳米夹。
J Neural Eng. 2017 Jun;14(3):036006. doi: 10.1088/1741-2552/aa5a5b. Epub 2017 Mar 21.
10
Neural interfaces for regenerated nerve stimulation and recording.用于再生神经刺激和记录的神经接口。
IEEE Trans Rehabil Eng. 1998 Dec;6(4):353-63. doi: 10.1109/86.736149.

引用本文的文献

1
Critical key points for anesthesia in experimental research involving sheep ().绵羊实验研究麻醉的关键要点()。
Open Vet J. 2024 Sep;14(9):2129-2137. doi: 10.5455/OVJ.2024.v14.i9.2. Epub 2024 Sep 30.
2
System of Implantable Electrodes for Neural Signal Acquisition and Stimulation for Wirelessly Connected Forearm Prosthesis.用于神经信号采集和刺激的植入式电极系统,用于无线连接的前臂假肢。
Biosensors (Basel). 2024 Jan 9;14(1):31. doi: 10.3390/bios14010031.

本文引用的文献

1
Fabrication of titanium dioxide nanomaterial for implantable highly flexible composite bioelectrode for biosensing applications.用于生物传感应用的可植入高柔性复合生物电极的二氧化钛纳米材料的制备。
Chemosphere. 2021 Jun;273:129680. doi: 10.1016/j.chemosphere.2021.129680. Epub 2021 Jan 18.
2
Tissue Response to Neural Implants: The Use of Model Systems Toward New Design Solutions of Implantable Microelectrodes.组织对神经植入物的反应:利用模型系统寻求可植入微电极的新设计解决方案
Front Neurosci. 2019 Jul 5;13:689. doi: 10.3389/fnins.2019.00689. eCollection 2019.
3
Glial responses to implanted electrodes in the brain.
大脑中胶质细胞对植入电极的反应。
Nat Biomed Eng. 2017 Nov;1(11):862-877. doi: 10.1038/s41551-017-0154-1. Epub 2017 Nov 10.
4
Update on Peripheral Nerve Electrodes for Closed-Loop Neuroprosthetics.用于闭环神经假体的周围神经电极的最新进展
Front Neurosci. 2018 May 28;12:350. doi: 10.3389/fnins.2018.00350. eCollection 2018.
5
An Implantable Wireless Neural Interface System for Simultaneous Recording and Stimulation of Peripheral Nerve with a Single Cuff Electrode.一种可植入的无线神经接口系统,用于通过单个袖套电极同时记录和刺激周围神经。
Sensors (Basel). 2017 Dec 21;18(1):1. doi: 10.3390/s18010001.
6
Restoration of motor control and proprioceptive and cutaneous sensation in humans with prior upper-limb amputation via multiple Utah Slanted Electrode Arrays (USEAs) implanted in residual peripheral arm nerves.通过在残留的外周臂神经中植入多个犹他斜电极阵列(USEA),使先前上肢截肢的人类恢复运动控制以及本体感受和皮肤感觉。
J Neuroeng Rehabil. 2017 Nov 25;14(1):121. doi: 10.1186/s12984-017-0320-4.
7
Tunable nanostructured conducting polymers for neural interface applications.用于神经接口应用的可调谐纳米结构导电聚合物。
Annu Int Conf IEEE Eng Med Biol Soc. 2017 Jul;2017:1881-1884. doi: 10.1109/EMBC.2017.8037214.
8
Invasive Intraneural Interfaces: Foreign Body Reaction Issues.侵入性神经内接口:异物反应问题。
Front Neurosci. 2017 Sep 6;11:497. doi: 10.3389/fnins.2017.00497. eCollection 2017.
9
Clinical applications of penetrating neural interfaces and Utah Electrode Array technologies.穿透性神经接口和犹他电极阵列技术的临床应用
J Neural Eng. 2016 Dec;13(6):061003. doi: 10.1088/1741-2560/13/6/061003. Epub 2016 Oct 20.
10
Multifunctional hydrogel coatings on the surface of neural cuff electrode for improving electrode-nerve tissue interfaces.用于改善电极-神经组织界面的神经袖套电极表面多功能水凝胶涂层
Acta Biomater. 2016 Jul 15;39:25-33. doi: 10.1016/j.actbio.2016.05.009. Epub 2016 May 6.