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光泵氦磁力计与传统超导量子干涉仪的性能分析：从成人到婴儿头部模型

Performance Analysis of Optically Pumped He Magnetometers vs. Conventional SQUIDs: From Adult to Infant Head Models.

作者信息

Zahran Saeed, Mahmoudzadeh Mahdi, Wallois Fabrice, Betrouni Nacim, Derambure Philippe, Le Prado Matthieu, Palacios-Laloy Agustin, Labyt Etienne

机构信息

INSERM, U1105, GRAMFC, Université de Picardie Jules Verne, CHU Sud, 80000 Amiens, France.

INSERM, U1172, CHU de Lille, Université de Lille, Degenerative & Vascular Cognitive Disorders, 59000 Lille, France.

出版信息

Sensors (Basel). 2022 Apr 18;22(8):3093. doi: 10.3390/s22083093.

DOI:10.3390/s22083093
PMID:35459077
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9024855/
Abstract

Optically pumped magnetometers (OPMs) are new, room-temperature alternatives to superconducting quantum interference devices (SQUIDs) for measuring the brain's magnetic fields. The most used OPM in MagnetoEncephaloGraphy (MEG) are based on alkali atoms operating in the spin-exchange relaxation-free (SERF) regime. These sensors do not require cooling but have to be heated. Another kind of OPM, based on the parametric resonance of He atoms are operated at room temperature, suppressing the heat dissipation issue. They also have an advantageous bandwidth and dynamic range more suitable for MEG recordings. We quantitatively assessed the improvement (relative to a SQUID magnetometers array) in recording the magnetic field with a wearable He OPM-MEG system through data simulations. The OPM array and magnetoencephalography forward models were based on anatomical MRI data from an adult, a nine-year-old child, and 10 infants aged between one month and two years. Our simulations showed that a He OPMs array offers markedly better spatial specificity than a SQUID magnetometers array in various key performance areas (e.g., signal power, information content, and spatial resolution). Our results are also discussed regarding previous simulation results obtained for alkali OPM.

摘要

光泵磁力仪（OPM）是用于测量脑磁场的超导量子干涉器件（SQUID）的新型室温替代品。在脑磁图（MEG）中最常用的OPM基于在无自旋交换弛豫（SERF）状态下运行的碱金属原子。这些传感器不需要冷却，但必须加热。另一种基于氦原子参数共振的OPM在室温下运行，解决了散热问题。它们还具有更适合MEG记录的有利带宽和动态范围。我们通过数据模拟定量评估了使用可穿戴式氦OPM-MEG系统记录磁场相对于SQUID磁力仪阵列的改进。OPM阵列和脑磁图正向模型基于一名成年人、一名九岁儿童以及10名年龄在1个月至2岁之间婴儿的解剖学MRI数据。我们的模拟表明，在各种关键性能领域（例如信号功率、信息含量和空间分辨率），氦OPM阵列比SQUID磁力仪阵列具有明显更好的空间特异性。我们还结合之前针对碱金属OPM获得的模拟结果对我们的结果进行了讨论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1161/9024855/6912374fa007/sensors-22-03093-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1161/9024855/c318d8c7a012/sensors-22-03093-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1161/9024855/b0e21c2f6dc8/sensors-22-03093-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1161/9024855/a06daa30ad28/sensors-22-03093-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1161/9024855/fea96e09ffa0/sensors-22-03093-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1161/9024855/1887d107ea87/sensors-22-03093-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1161/9024855/72903ff7a100/sensors-22-03093-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1161/9024855/b82d3b96ef8d/sensors-22-03093-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1161/9024855/6912374fa007/sensors-22-03093-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1161/9024855/c318d8c7a012/sensors-22-03093-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1161/9024855/b0e21c2f6dc8/sensors-22-03093-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1161/9024855/a06daa30ad28/sensors-22-03093-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1161/9024855/fea96e09ffa0/sensors-22-03093-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1161/9024855/1887d107ea87/sensors-22-03093-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1161/9024855/72903ff7a100/sensors-22-03093-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1161/9024855/b82d3b96ef8d/sensors-22-03093-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1161/9024855/6912374fa007/sensors-22-03093-g008.jpg

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