SUNY Downstate College of Medicine, Brooklyn, NY, USA.
Department of Neurological Surgery, Lenox Hill Hospital, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New York, NY, USA.
Spinal Cord Ser Cases. 2022 Apr 22;8(1):43. doi: 10.1038/s41394-022-00513-x.
Spinal myxopapillary ependymomas (SME) are rare WHO grade II neoplasms of the spinal cord. Despite their good prognosis, they have a high propensity for metastasis and recurrence, although the presentation of SME as multifocal is uncommon.
Here we describe a rare case of a 34-year-old man who presented with painful bilateral radiculopathy with sexual dysfunction and altered sensation with defecation. The patient also reported worsening weakness of bilateral lower extremities when climbing stairs. Biopsy results revealed multifocal SME in the lumbar and sacral spine that was treated with staged surgical resection and post-operative focal radiation therapy.
We discuss and evaluate surgical resection and the role of postoperative radiotherapy for SME. We also review the literature surrounding multifocal SME presenting in adults.
脊髓黏液乳头型室管膜瘤（SME）是一种罕见的脊髓中枢神经系统二级肿瘤。尽管它们的预后良好，但具有较高的转移和复发倾向，尽管 SME 呈现多灶性并不常见。
在这里，我们描述了一个罕见的病例，一名 34 岁男性患者出现双侧神经根痛、性功能障碍、排便感觉改变，同时还报告称在爬楼梯时双侧下肢无力加重。活检结果显示腰椎和骶骨的多灶性 SME，采用分期手术切除和术后局部放疗进行治疗。
我们讨论并评估了 SME 的手术切除和术后放疗的作用。我们还回顾了成人多灶性 SME 的文献。
