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脊髓黏液乳头型室管膜瘤伴间歇性播散性转移表现为马尾综合征:病例报告及文献复习

Spinal myxopapillary ependymoma with interval drop metastasis presenting as cauda equina syndrome: case report and review of literature.

作者信息

Rege Shrikant V, Narayan Sharadendu, Patil Harshad, Songara Abhishek

机构信息

Sri Aurobindo Medical College and P.G Institute, Indore, India.

出版信息

J Spine Surg. 2016 Sep;2(3):216-221. doi: 10.21037/jss.2016.08.06.

Abstract

Myxopapillary ependymoma is a benign slow-growing tumour, arising predominantly in the region of the filum terminale. It has been designated histologically as grade I neoplasm according to the 2007 WHO classification. Despite this benign character dissemination and metastasis along the cerebrospinal axis and metastasis to distant sites have occasionally been reported. There have been previously reported cases of drop metastasis from MPE, however in three of these cases the drop metastasis was diagnosed with concurrent primary spinal MPE. There has been only one previously published case of interval drop metastasis in a case of operated spinal MPE in literature. We hereby present the second case of interval drop metastasis in a case of conus MPE, with history of having undergone a subtotal resection and post operative adjuvant radiotherapy prior to second surgery. The patient presented months after the primary surgery with symptoms of cauda equina syndrome attributable to the drop metastasis.

摘要

黏液乳头型室管膜瘤是一种生长缓慢的良性肿瘤,主要发生于终丝区域。根据2007年世界卫生组织分类,其组织学上被定为I级肿瘤。尽管具有这种良性特征,但沿脑脊轴的播散和转移以及远处转移偶尔也有报道。此前曾有黏液乳头型室管膜瘤发生播散性转移的病例报道,然而在其中3例中,播散性转移是在同时存在原发性脊髓黏液乳头型室管膜瘤的情况下被诊断出来的。在文献中,之前仅有1例已手术的脊髓黏液乳头型室管膜瘤发生间隔性播散性转移的病例报道。在此,我们报告第二例圆锥黏液乳头型室管膜瘤发生间隔性播散性转移的病例,该患者在二次手术前有次全切除病史及术后辅助放疗史。患者在初次手术后数月出现马尾神经综合征症状,系由播散性转移所致。

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