Specific targeting of lung ILC2s via NRP1 in pulmonary fibrosis.
作者信息
Nii Takuro, Fukushima Kiyoharu, Kida Hiroshi
机构信息
Department of Respiratory Medicine, National Hospital Organization Osaka Toneyama Medical Center, 5-1-1 Toneyama, Osaka, Japan.
Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, Japan.
出版信息
Cell Mol Immunol. 2022 Aug;19(8):869-871. doi: 10.1038/s41423-022-00867-0. Epub 2022 Apr 22.
Abstract
摘要
相似文献
1
Specific targeting of lung ILC2s via NRP1 in pulmonary fibrosis.通过神经纤毛蛋白1（NRP1）特异性靶向肺中的2型固有淋巴细胞（ILC2s）以治疗肺纤维化
Cell Mol Immunol. 2022 Aug;19(8):869-871. doi: 10.1038/s41423-022-00867-0. Epub 2022 Apr 22.
2
Neuropilin-1 mediates lung tissue-specific control of ILC2 function in type 2 immunity.神经纤毛蛋白-1介导 2 型免疫中 ILC2 功能的肺组织特异性调控。
Nat Immunol. 2022 Feb;23(2):237-250. doi: 10.1038/s41590-021-01097-8. Epub 2022 Jan 24.
3
NRP1 downregulation correlates with enhanced ILC2 responses during IL-33 challenge.NRP1 的下调与 IL-33 刺激期间增强的 ILC2 反应相关。
Immunology. 2024 Jun;172(2):226-234. doi: 10.1111/imm.13769. Epub 2024 Feb 26.
4
CD45 alleviates airway inflammation and lung fibrosis by limiting expansion and activation of ILC2s.CD45 通过限制 ILC2 的扩增和激活来缓解气道炎症和肺纤维化。
Proc Natl Acad Sci U S A. 2023 Sep 5;120(36):e2215941120. doi: 10.1073/pnas.2215941120. Epub 2023 Aug 28.
5
Type 2 innate immunity promotes the development of pulmonary fibrosis in Hermansky-Pudlak syndrome.2 型先天免疫促进 Hermansky-Pudlak 综合征肺纤维化的发展。
JCI Insight. 2024 Nov 22;9(22):e178381. doi: 10.1172/jci.insight.178381.
6
Profibrotic function of pulmonary group 2 innate lymphoid cells is controlled by regnase-1.肺 2 型固有淋巴细胞的促纤维生成功能受 Regnase-1 调控。
Eur Respir J. 2021 Mar 11;57(3). doi: 10.1183/13993003.00018-2020. Print 2021 Mar.
7
Activation of ILC2s through constitutive IFNγ signaling reduction leads to spontaneous pulmonary fibrosis.通过组成性 IFNγ 信号降低激活 ILC2s 会导致自发性肺纤维化。
Nat Commun. 2023 Dec 14;14(1):8120. doi: 10.1038/s41467-023-43336-6.
8
An ST2-dependent role of bone marrow-derived group 2 innate lymphoid cells in pulmonary fibrosis.骨髓源性 2 型固有淋巴细胞在肺纤维化中的 ST2 依赖性作用。
J Pathol. 2018 Aug;245(4):399-409. doi: 10.1002/path.5092. Epub 2018 Jun 5.
9
Type 2 innate lymphoid cell counts are increased in patients with systemic sclerosis and correlate with the extent of fibrosis.2 型固有淋巴细胞计数在系统性硬化症患者中增加，并与纤维化程度相关。
Ann Rheum Dis. 2016 Mar;75(3):623-6. doi: 10.1136/annrheumdis-2015-207388. Epub 2015 Sep 2.
10
Group 2 innate lymphoid cells contribute to IL-33-mediated alleviation of cardiac fibrosis.2 型固有淋巴细胞有助于 IL-33 介导的心脏纤维化缓解。
Theranostics. 2021 Jan 1;11(6):2594-2611. doi: 10.7150/thno.51648. eCollection 2021.
引用本文的文献
1
Tissue microenvironment induces tissue specificity of ILC2.组织微环境诱导2型固有淋巴细胞的组织特异性。
Cell Death Discov. 2024 Jul 16;10(1):324. doi: 10.1038/s41420-024-02096-y.
本文引用的文献
1
Neuropilin-1 mediates lung tissue-specific control of ILC2 function in type 2 immunity.神经纤毛蛋白-1介导 2 型免疫中 ILC2 功能的肺组织特异性调控。
Nat Immunol. 2022 Feb;23(2):237-250. doi: 10.1038/s41590-021-01097-8. Epub 2022 Jan 24.
2
Innate Lymphoid Cells in Autoimmune Diseases.固有淋巴细胞在自身免疫性疾病中的作用。
Front Immunol. 2022 Jan 7;12:789788. doi: 10.3389/fimmu.2021.789788. eCollection 2021.
3
The Role of Type 2 Innate Lymphoid Cells in Allergic Diseases.2 型固有淋巴细胞在过敏性疾病中的作用。
Front Immunol. 2021 Jun 9;12:586078. doi: 10.3389/fimmu.2021.586078. eCollection 2021.
4
Tissue-specific transcriptional imprinting and heterogeneity in human innate lymphoid cells revealed by full-length single-cell RNA-sequencing.全长单细胞 RNA 测序揭示人类固有淋巴细胞中的组织特异性转录印迹和异质性。
Cell Res. 2021 May;31(5):554-568. doi: 10.1038/s41422-020-00445-x. Epub 2021 Jan 8.
5
Profibrotic function of pulmonary group 2 innate lymphoid cells is controlled by regnase-1.肺 2 型固有淋巴细胞的促纤维生成功能受 Regnase-1 调控。
Eur Respir J. 2021 Mar 11;57(3). doi: 10.1183/13993003.00018-2020. Print 2021 Mar.
6
Dysregulated Expression of the Nuclear Exosome Targeting Complex Component Rbm7 in Nonhematopoietic Cells Licenses the Development of Fibrosis.核体靶向复合物成分 Rbm7 在非造血细胞中的失调表达可促进纤维化的发生。
Immunity. 2020 Mar 17;52(3):542-556.e13. doi: 10.1016/j.immuni.2020.02.007.
7
Targeting interleukin-13 in idiopathic pulmonary fibrosis: from promising path to dead end.针对白细胞介素-13治疗特发性肺纤维化：从充满希望的道路到死胡同。
Eur Respir J. 2018 Dec 13;52(6). doi: 10.1183/13993003.02111-2018. Print 2018 Dec.
8
Tissue signals imprint ILC2 identity with anticipatory function.组织信号预先赋予 ILC2 身份。
Nat Immunol. 2018 Oct;19(10):1093-1099. doi: 10.1038/s41590-018-0201-4. Epub 2018 Sep 10.
9
Innate Lymphoid Cells: 10 Years On.先天淋巴细胞：十年进展。
Cell. 2018 Aug 23;174(5):1054-1066. doi: 10.1016/j.cell.2018.07.017.
10
Identification of an atypical monocyte and committed progenitor involved in fibrosis.鉴定一种参与纤维化的非典型单核细胞和定向祖细胞。
Nature. 2017 Jan 5;541(7635):96-101. doi: 10.1038/nature20611. Epub 2016 Dec 21.
Zotero 插件