Svetikova K M
Arkh Anat Gistol Embriol. 1978 Apr;74(4):63-9.
Proliferative processes were studied in epithelial cells of skin autografts and the surrounding skin in mice of CBA line. In the animals subjected to the operation but without cortisone injection (Fig. 1, a and Fig. 2, delta), a high proliferative activity in the skin epithelial cells surrounding the autograft was observed during the whole course of the experiment. In the cells of the autograft, the mitotic activity, after inhibition, restored quickly up to the original level, and in 10 days it sharply increased and did not differ from that in the epithelium of the surrounding skin. The amount of DNA-synthesising cells in the epithlium of the autograft at first remained at the original level, and then, after a short sharp rise, it decreased up to its level in the surrounding skin and then was changing nearly in the similar fashion with it. After repeated injection of cortisone both indices of proliferative activity (Fig 1, delta and Fig. 2, delta) in the epithlium of the autograft and of the surrounding skin gradually increased although slower than in the controls.
对CBA系小鼠自体皮肤移植片及其周围皮肤的上皮细胞增殖过程进行了研究。在接受手术但未注射可的松的动物中（图1a和图2δ），在整个实验过程中，观察到自体移植片周围皮肤上皮细胞具有较高的增殖活性。在自体移植片的细胞中，有丝分裂活性在受到抑制后迅速恢复到原始水平，并且在10天时急剧增加，与周围皮肤上皮中的有丝分裂活性没有差异。自体移植片上皮中DNA合成细胞的数量起初保持在原始水平，然后在短暂急剧上升后，下降至周围皮肤中的水平，然后与周围皮肤以几乎相似的方式变化。反复注射可的松后，自体移植片和周围皮肤上皮中的增殖活性指标（图1δ和图2δ）逐渐增加，尽管比对照组增加得慢。
