Institute of Innovation, Science and Sustainability, Federation University, Churchill, Australia.
School of Biological Sciences, Monash University, Melbourne, Victoria, Australia.
Zoonoses Public Health. 2022 Sep;69(6):615-624. doi: 10.1111/zph.12950. Epub 2022 Apr 22.
Antibiotic resistance is an ongoing threat to both human and animal health. Migratory birds are a potential vector for the spread of novel pathogens and antibiotic resistance genes. To date, there has been no comprehensive study investigating the presence of antibiotic resistance (AMR) in the bacteria of Australian shorebirds or terns. In the current study, 1022 individual birds representing 12 species were sampled across three states of Australia (Victoria, South Australia, and Western Australia) and tested for the presence of phenotypically resistant strains of three bacteria with potential to be zoonotic pathogens; Escherichia coli, Enterococcusspp., and Salmonellasp. In total, 206 E. coli, 266 Enterococcusspp., and 20 Salmonellasp. isolates were recovered, with AMR detected in 42% of E. coli, 85% of Enterococcusspp., and 10% of Salmonellasp. Phenotypic resistance was commonly detected to erythromycin (79% of Enterococcusspp.), ciprofloxacin (31% of Enterococcusspp.) and streptomycin (21% of E. coli). Resident birds were more likely to carry AMR bacteria than migratory birds (p ≤ .001). Bacteria isolated from shorebirds and terns are commonly resistant to at least one antibiotic, suggesting that wild bird populations serve as a potential reservoir and vector for AMR bacteria. However, globally emerging phenotypes of multidrug-resistant bacteria were not detected in Australian shorebirds. This study provides baseline data of the carriage of AMR bacteria in Australian shorebirds and terns.
抗生素耐药性是人类和动物健康的持续威胁。候鸟是新型病原体和抗生素耐药基因传播的潜在载体。迄今为止，还没有全面研究调查澳大利亚滨鸟或燕鸥细菌中抗生素耐药性（AMR）的存在。在当前的研究中，在澳大利亚的三个州（维多利亚州、南澳大利亚州和西澳大利亚州），对代表 12 个物种的 1022 只个体鸟类进行了采样，并对 3 种具有潜在人畜共患病病原体的细菌的表型耐药菌株进行了检测；大肠杆菌、肠球菌和沙门氏菌。总共回收了 206 株大肠杆菌、266 株肠球菌和 20 株沙门氏菌，其中 42%的大肠杆菌、85%的肠球菌和 10%的沙门氏菌存在 AMR。表型耐药性通常检测到红霉素（79%的肠球菌）、环丙沙星（31%的肠球菌）和链霉素（21%的大肠杆菌）。留鸟比候鸟更容易携带 AMR 细菌（p ≤ .001）。从滨鸟和燕鸥中分离出的细菌通常对至少一种抗生素具有耐药性，这表明野生鸟类种群可能是 AMR 细菌的潜在储存库和传播媒介。然而，在澳大利亚的滨鸟中没有检测到全球新兴的多药耐药细菌表型。本研究提供了澳大利亚滨鸟和燕鸥携带 AMR 细菌的基线数据。
