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生物体液中百草枯的应急分析

Emergency analysis of paraquat in biological fluids.

作者信息

Braithwaite R A

出版信息

Hum Toxicol. 1987 Jan;6(1):83-6. doi: 10.1177/096032718700600113.

DOI:10.1177/096032718700600113
PMID:3546090
Abstract

A variety of spectrophotometric, gas and liquid chromatographic and radioimmunoassay techniques have been applied to the measurement of paraquat in biological fluids. A brief review of these techniques is presented. The majority of described methods are far from suitable in the provision of an accurate and reliable quantitative result in an emergency situation and the further development of suitable 'rapid' techniques is desirable. The preparation and characterisation of internal accuracy control materials and the introduction of an external quality assessment scheme would be valuable in the improvement of laboratory investigations of paraquat poisoning.

摘要

多种分光光度法、气相和液相色谱法以及放射免疫测定技术已应用于生物体液中百草枯的测量。本文对这些技术进行简要综述。大多数已描述的方法远不适用于在紧急情况下提供准确可靠的定量结果,因此需要进一步开发合适的“快速”技术。制备和表征内部准确度控制材料以及引入外部质量评估方案对于改进百草枯中毒的实验室检测将具有重要价值。

相似文献

1
Emergency analysis of paraquat in biological fluids.生物体液中百草枯的应急分析
Hum Toxicol. 1987 Jan;6(1):83-6. doi: 10.1177/096032718700600113.
2
The determination of paraquat.百草枯的测定
J Chromatogr Sci. 1978 Sep;16(9):390-5. doi: 10.1093/chromsci/16.9.390.
3
Gas--liquid chromatographic assay of aminoglutethimide and a high-performance liquid chromatographic assay for its acetyl metabolite in biological fluids.生物流体中氨鲁米特的气相色谱分析及其乙酰代谢物的高效液相色谱分析。
J Chromatogr. 1984 Apr 13;307(1):129-35. doi: 10.1016/s0378-4347(00)84079-7.
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Reverse-phase liquid chromatographic determination of paraquat and diquat in agricultural products.反相液相色谱法测定农产品中的百草枯和敌草快
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[Toxicological determination, pathogenesis and time relation of changes following acute Gramoxone (paraquat0 poisoning. I. Toxicological determination of poisoning].急性克芜踪(百草枯)中毒后变化的毒理学测定、发病机制及时间关系。I. 中毒的毒理学测定
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[Progress in research on paraquat determination method].[百草枯测定方法的研究进展]
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A case of fatal paraquat poisoning and a rapid method for analysis of paraquat in biological material.一例致命性百草枯中毒病例及生物材料中百草枯的快速分析方法。
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Simultaneous determination of paraquat and diquat in human tissues by high-performance liquid chromatography.高效液相色谱法同时测定人体组织中的百草枯和敌草快
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Analysis for paraquat by second- and fourth-derivative spectroscopy.
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Retention indices and dual capillary gas chromatography for rapid identification of sedative hypnotic drugs in emergency toxicology.保留指数和双毛细管气相色谱法在急诊毒理学中快速鉴定镇静催眠药物的应用
J Anal Toxicol. 1984 May-Jun;8(3):129-34. doi: 10.1093/jat/8.3.129.

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The time between paraquat ingestion and a negative dithionite urine test in an independent risk factor for death and organ failure in acute paraquat intoxication.百草枯中毒后至二硫代硫酸钠尿液检测阴性的时间是急性百草枯中毒死亡和器官衰竭的独立危险因素。
J Korean Med Sci. 2012 Sep;27(9):993-8. doi: 10.3346/jkms.2012.27.9.993. Epub 2012 Aug 22.
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The poison pen: bedside diagnosis of urinary diquat.毒笔:床边诊断尿路百草枯。
J Med Toxicol. 2010 Mar;6(1):35-6. doi: 10.1007/s13181-010-0033-6.
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Pulse therapy with cyclophosphamide and methylprednisolone in patients with moderate to severe paraquat poisoning: a preliminary report.环磷酰胺与甲泼尼龙脉冲疗法治疗中重度百草枯中毒患者:初步报告
Thorax. 1996 Jul;51(7):661-3. doi: 10.1136/thx.51.7.661.