Chan A S, Tang K C, Fung K K, Ng T K
Infection. 1986;14 Suppl 4:S314-5. doi: 10.1007/BF01661305.
78 patients (66 male and 12 female) suffering from uncomplicated gonorrhoea were randomly selected to receive a single oral dose of either 400 mg or 600 mg ofloxacin. Of the 59 patients completely followed up penicillinase-producing Neisseria gonorrhoeae strains were cultured in 15 (25.4%) and the overall cure rate was 100%. Both groups showed excellent clinical effectiveness in over 80% and adverse reactions were uncommon and transient. We conclude that a single oral dose of ofloxacin in the studied dosage regimens was highly effective and safe in the treatment of uncomplicated gonorrhoea.