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眼见不一定为实:甲状腺手术中的术中神经监测(IONM)

Seeing Is Not Believing: Intraoperative Nerve Monitoring (IONM) in the Thyroid Surgery.

作者信息

Deshmukh Anuja, Thomas Anand Ebin, Dhar Harsh, Velayutham Parthiban, Pantvaidya Gouri, Pai Prathamesh, Chaukar Devendra

机构信息

Department of Head and Neck Oncology, Tata Memorial Centre, Parel, Mumbai, Maharashtra 400012 India.

Department of Surgical Oncology, Malabar Cancer Centre, Thalassery, Kerala 670103 India.

出版信息

Indian J Surg Oncol. 2022 Mar;13(1):121-132. doi: 10.1007/s13193-021-01348-y. Epub 2021 May 17.

Abstract

Ensuring the integrity of the recurrent laryngeal nerve (RLN), the external branch of superior laryngeal nerve (EBSLN) and preservation of normal voice are the prime 'functional' goals of thyroid surgery. More in-depth knowledge of neuronal mechanisms has revealed that anatomical integrity does not always translate into functional integrity. Despite meticulous dissection, neural injuries are not always predictable or visually evident. Intraoperative nerve monitoring (IONM) is designed to aid in nerve identification and early detection of functional impairment. With the evolution of technique, intermittent monitoring has given way to continuous-IONM. Over the years, IONM gathered both support and flak. Despite numerous randomised studies, systematic reviews, and meta-analyses, there still prevails a state of clinical equipoise concerning the utility of IONM and its cost-effectiveness. This article inspects the true usefulness of IONM, elaborates on the optimal way to practice it, and presents a critical literature review.

摘要

确保喉返神经(RLN)、喉上神经外支(EBSLN)的完整性以及保持正常嗓音是甲状腺手术的首要“功能”目标。对神经机制更深入的了解表明,解剖学完整性并不总是能转化为功能完整性。尽管进行了细致的解剖,但神经损伤并不总是可预测的或肉眼可见的。术中神经监测(IONM)旨在辅助神经识别和早期发现功能损害。随着技术的发展,间歇性监测已被连续术中神经监测所取代。多年来,术中神经监测既得到了支持,也受到了抨击。尽管有大量的随机研究、系统评价和荟萃分析,但关于术中神经监测的效用及其成本效益,临床 equipoise 状态仍然存在。本文探讨了术中神经监测的真正效用,阐述了实施它的最佳方法,并进行了批判性的文献综述。

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