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喉返神经术中神经监测在甲状腺和甲状旁腺手术中的作用

Role of intraoperative neuromonitoring of recurrent laryngeal nerve in thyroid and parathyroid surgery.

作者信息

Ling Yuwei, Zhao Jing, Zhao Ye, Li Kaifu, Wang Yajun, Kang Hua

机构信息

Center for Thyroid and Breast Surgery, Department of General Surgery, Xuanwu Hospital, Capital Medical University, Beijing, China.

出版信息

J Int Med Res. 2020 Sep;48(9):300060520952646. doi: 10.1177/0300060520952646.

Abstract

OBJECTIVE

To investigate whether intraoperative neuromonitoring (IONM) has a significant advantage in reducing the incidence of recurrent laryngeal nerve (RLN) injury.

METHODS

Patients who underwent thyroid and parathyroid surgery from October 2012 to December 2017 at the Center for Thyroid and Breast Surgery of Xuanwu Hospital were retrospectively analyzed. They were divided into the IONM group and visualization alone group (VA group) according to whether IONM was used.

RESULTS

In total, 1696 nerves at risk of injury (IONM group, n = 1104; VA group, n = 592) were included in the analysis. Among the high-risk nerves, permanent damage occurred in no cases in the IONM group but in one case in the VA group. Because the higher proportion of central lymph node metastasis caused difficulties in central cervical lymph node dissection and identification of the RLN, the patients undergoing lateral cervical lymph node dissection in the VA group had a significantly higher risk of postoperative RLN injury (11.76% vs. 0.00%).

CONCLUSION

IONM technology has advantages in protection of the RLN, especially in high-risk nerves and patients with a high proportion of central lymph node metastasis who require central and lateral cervical lymph node dissection.

摘要

目的

探讨术中神经监测(IONM)在降低喉返神经(RLN)损伤发生率方面是否具有显著优势。

方法

回顾性分析2012年10月至2017年12月在宣武医院甲状腺乳腺外科中心接受甲状腺和甲状旁腺手术的患者。根据是否使用IONM将他们分为IONM组和单纯可视化组(VA组)。

结果

分析共纳入1696条有损伤风险的神经(IONM组,n = 1104;VA组,n = 592)。在高危神经中,IONM组无永久性损伤病例,而VA组有1例。由于中央淋巴结转移比例较高导致中央颈部淋巴结清扫和RLN识别困难,VA组接受侧颈部淋巴结清扫的患者术后RLN损伤风险显著更高(11.76%对0.00%)。

结论

IONM技术在保护RLN方面具有优势,尤其是在高危神经以及需要进行中央和侧颈部淋巴结清扫的中央淋巴结转移比例较高的患者中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/582f/7513400/2eeeafb6cba7/10.1177_0300060520952646-fig1.jpg

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