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脑深部电刺激术后并发症:426例患者的21年经验

Complications After Deep Brain Stimulation: A 21-Year Experience in 426 Patients.

作者信息

Jung In-Ho, Chang Kyung Won, Park So Hee, Chang Won Seok, Jung Hyun Ho, Chang Jin Woo

机构信息

Department of Neurosurgery, Brain Research Institute, Yonsei University College of Medicine, Seoul, South Korea.

Department of Neurosurgery, Dankook University College of Medicine, Cheonan, South Korea.

出版信息

Front Aging Neurosci. 2022 Apr 7;14:819730. doi: 10.3389/fnagi.2022.819730. eCollection 2022.

DOI:10.3389/fnagi.2022.819730
PMID:35462695
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9022472/
Abstract

BACKGROUND

Deep brain stimulation is an established treatment for movement disorders such as Parkinson's disease, essential tremor, and dystonia. However, various complications that occur after deep brain stimulation are a major concern for patients and neurosurgeons.

OBJECTIVE

This study aimed to analyze various complications that occur after deep brain stimulation.

METHODS

We reviewed the medical records of patients with a movement disorder who underwent bilateral deep brain stimulation between 2000 and 2020. Among them, patients requiring revision surgery were analyzed.

RESULTS

A total of 426 patients underwent bilateral deep brain stimulation for a movement disorder. The primary disease was Parkinson's disease in 315 patients, followed by dystonia in 71 patients and essential tremor in 40 patients. Twenty-six (6.1%) patients had complications requiring revision surgery; the most common complication was infection (12 patients, 2.8%).

CONCLUSION

Various complications may occur after deep brain stimulation, and patient prognosis should be improved by reducing complications.

摘要

背景

脑深部电刺激是治疗帕金森病、特发性震颤和肌张力障碍等运动障碍的既定疗法。然而,脑深部电刺激术后出现的各种并发症是患者和神经外科医生主要关注的问题。

目的

本研究旨在分析脑深部电刺激术后出现的各种并发症。

方法

我们回顾了2000年至2020年间接受双侧脑深部电刺激的运动障碍患者的病历。其中,对需要翻修手术的患者进行了分析。

结果

共有426例患者因运动障碍接受了双侧脑深部电刺激。原发性疾病为帕金森病315例,其次是肌张力障碍71例,特发性震颤40例。26例(6.1%)患者出现需要翻修手术的并发症;最常见的并发症是感染(12例,2.8%)。

结论

脑深部电刺激术后可能会出现各种并发症,应通过减少并发症来改善患者预后。

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5
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9
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