Suppr超能文献

食用昆虫提取物的表征、抗氧化活性及对胰脂肪酶的抑制作用

Characterization, Antioxidant Activities, and Pancreatic Lipase Inhibitory Effect of Extract From the Edible Insect .

作者信息

Zhang Zongqi, Chen Sicong, Wei Xunfan, Xiao Jinhua, Huang Dawei

机构信息

College of Life Sciences, Nankai University, Tianjin, China.

出版信息

Front Nutr. 2022 Apr 7;9:860174. doi: 10.3389/fnut.2022.860174. eCollection 2022.

Abstract

Oxidative stress and obesity are critical risk factors for metabolic syndrome. The consumption of functional food ingredients can a viable strategy to alleviate oxidative stress and obesity. In this study, the hydro-ethanolic extract of the edible insect was prepared and its bioactive components were characterized. The total polyphenol contents, total flavonoid contents, antioxidant and pancreatic lipase (PL) inhibitory activities of the extract were determined . In total, 60 bioactive components were tentatively identified in the extract. Polyphenols and fatty acids were further quantified using LC-MS and GC-MS, respectively. extract possessed excellent antioxidant and PL inhibition activities. Salicylic acid, gallic acid, liquiritigenin, and naringenin, which were the major polyphenols in the extract, interacted with PL through hydrogen bonding, hydrophilic or hydrophobic and pi-cation interactions. Thus, extract can be used as a nutraceutical to alleviate oxidative stress-induced disease and manage obesity.

摘要

氧化应激和肥胖是代谢综合征的关键风险因素。食用功能性食品成分可能是缓解氧化应激和肥胖的一种可行策略。在本研究中,制备了食用昆虫的水乙醇提取物,并对其生物活性成分进行了表征。测定了提取物的总多酚含量、总黄酮含量、抗氧化和胰脂肪酶(PL)抑制活性。提取物中总共初步鉴定出60种生物活性成分。分别使用液相色谱-质谱联用仪(LC-MS)和气相色谱-质谱联用仪(GC-MS)对多酚和脂肪酸进行了进一步定量。提取物具有优异的抗氧化和PL抑制活性。提取物中的主要多酚水杨酸、没食子酸、甘草素和柚皮苷通过氢键、亲水或疏水以及π-阳离子相互作用与PL相互作用。因此,提取物可用作营养保健品,以缓解氧化应激诱导的疾病并控制肥胖。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed51/9021923/9b91a34e5ec4/fnut-09-860174-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验