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氟氯西林抑制5-氧脯氨酸酶导致一名肩关节假体关节感染患者发生严重酸中毒。

Severe acidosis due to 5-oxoprolinase inhibition by flucloxacillin in a patient with shoulder prosthesis joint infection.

作者信息

Lenz Julia Elisabeth, Alt Volker, Dienemann Thomas

机构信息

Department of Trauma Surgery, University Medical Center Regensburg, Regensburg, Germany.

Department of Surgery, Surgical Intensive Care Unit, University Medical Center Regensburg, Regensburg, Germany.

出版信息

J Bone Jt Infect. 2022 Apr 4;7(2):71-74. doi: 10.5194/jbji-7-71-2022. eCollection 2022.

Abstract

We report a case of a 64-year-old female patient with severe metabolic acidosis. Inhibition of 5-oxoprolinase by flucloxacillin was found to be the cause of the metabolic derailment.

摘要

我们报告一例64岁患有严重代谢性酸中毒的女性患者。发现氟氯西林对5-氧脯氨酸酶的抑制作用是代谢紊乱的原因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db5a/9022110/b3fb417e5678/jbji-7-71-g01.jpg

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