Institute of Neuroscience and Psychology, University of Glasgow, Glasgow, G12 8QB, UK.
Trends Cogn Sci. 2022 Jul;26(7):544-554. doi: 10.1016/j.tics.2022.03.010. Epub 2022 Apr 21.
The brain is highly segregated. Multiple mechanisms ensure that different types of memories are processed independently. Nonetheless, information leaks out across these memory systems. Only recently has the diversity of these leaks been revealed. Different memory types (skills vs. facts) can interact in simple ways, either allowing or preventing their further processing, or in more complex ways, allowing the sharing of abstract information between memories. Leaks occur from memories dependent upon hippocampal circuits, which have properties critical for leaks and activity patterns related to memory interactions. This hippocampal contribution is likely achieved in concert with cortical areas. Leaks between memories enable the application of knowledge in novel situations, explain learning dynamics, and solve important problems inherent to memory formation.
大脑具有高度的分区性。多种机制确保不同类型的记忆独立处理。尽管如此,信息仍会在这些记忆系统之间泄露。直到最近,这些泄露的多样性才被揭示出来。不同类型的记忆(技能与事实)可以以简单的方式相互作用,要么允许要么阻止它们的进一步处理,或者以更复杂的方式,允许在记忆之间共享抽象信息。泄露发生在依赖海马体回路的记忆中,这些回路具有关键的泄露特性和与记忆相互作用相关的活动模式。这种海马体的贡献可能与皮层区域协同实现。记忆之间的泄露使知识能够在新的情况下应用,解释学习动态,并解决记忆形成中固有的重要问题。