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肥胖症患者接受减肥手术后 2 年后过度饮酒的发生率及其相关危险因素。

Prevalence of and Risk Factors Associated with Alcohol Overconsumption at 2 Years After Bariatric Surgery.

机构信息

School of Medical Sciences, Örebro University, Örebro, Sweden.

Department Surgery, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.

出版信息

Obes Surg. 2022 Jul;32(7):1-6. doi: 10.1007/s11695-022-06060-6. Epub 2022 Apr 25.

Abstract

INTRODUCTION

Alcohol overconsumption remains one of the adverse effects associated with bariatric surgery. Many previous studies have used subjective methods to evaluate the prevalence of alcohol overconsumption. In 2018, Örebro University Hospital started to use phosphatidylethanol 16:0/18:1 (PEth) as a screening tool pre- and postbariatric surgery. Research exploring alcohol use after bariatric surgery assessed with PEth is scarce.

AIM

The aim of this study is to evaluate the prevalence of alcohol overconsumption in bariatric surgery patients measured 2 years postoperatively with PEth and to identify possible risk factors associated with alcohol overconsumption.

METHODS

This was a register-based retrospective, observational cohort study with PEth results collected from medical records at Örebro University Hospital. Patients who underwent bariatric surgery between January 2016 and June 2019 and who were registered in the Scandinavian Obesity Surgery Registry (SOReg) were included.

RESULTS

PEth results from 410 bariatric surgery patients were identified. PEth values significantly increased from baseline to the postoperative follow-up (from 3.0% before surgery to 8.3% at the 2-year follow-up). In a univariate logistic regression analysis, the associated risk factors were found to be male sex (odds ratio, OR 2.14), older age (OR 1.06), and hypertension (OR 3.32).

CONCLUSION

The prevalence of alcohol overconsumption measured with PEth 2 years after bariatric surgery was 8.3% and was associated with male sex, older age, and hypertension. More studies are needed to validate the results of this study because it is not known whether PEth values are affected by bariatric surgery.

摘要

简介

饮酒过量仍是与减重手术相关的不良影响之一。许多先前的研究使用主观方法评估酒精过量的发生率。2018 年,厄勒布鲁大学医院开始在减重手术前和手术后使用磷脂酰乙醇胺 16:0/18:1(PEth)作为筛查工具。使用 PEth 评估减重手术后饮酒情况的研究很少。

目的

本研究旨在评估使用 PEth 测量的 2 年后减重手术患者酒精过量的发生率,并确定与酒精过量相关的可能危险因素。

方法

这是一项基于登记的回顾性、观察性队列研究,PEth 结果从厄勒布鲁大学医院的病历中收集。纳入 2016 年 1 月至 2019 年 6 月期间接受减重手术且在斯堪的纳维亚肥胖手术登记处(SOReg)注册的患者。

结果

确定了 410 名减重手术患者的 PEth 结果。PEth 值从基线到术后随访显著增加(手术前为 3.0%,2 年随访时为 8.3%)。在单变量逻辑回归分析中,相关的危险因素为男性(比值比,OR 2.14)、年龄较大(OR 1.06)和高血压(OR 3.32)。

结论

使用 PEth 测量的 2 年后减重手术后酒精过量的发生率为 8.3%,与男性、年龄较大和高血压有关。需要更多的研究来验证本研究的结果,因为尚不清楚 PEth 值是否受减重手术的影响。

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High-risk alcohol use after weight loss surgery.减肥手术后的高风险酒精使用。
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