School of Public Health, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia.
Department of Midwifery, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia.
PLoS One. 2022 Apr 26;17(4):e0266054. doi: 10.1371/journal.pone.0266054. eCollection 2022.
Hyperemesis gravidarum is severe nausea and excessive vomiting, starting between 4 and 6 gestational weeks, peak at between 8 and 12 weeks and usually improve and subside by 20 weeks of pregnancy. Identifying the determinants of hyperemesis gravidarum has a particular importance for early detection and intervention to reduce the health, psychosocial and economic impact. In Ethiopia there is low information on determinants of hyperemesis gravidarum.
Institution based unmatched case-control study design was conducted from April 12- June 12, 2021. A structured face-to-face interviewer administered questionnaire and checklist for document review were used to collect the data from 360 study participants (120 cases and 240 controls). The data were collected by KoBocollect 1.3, and then exported to statistical package for social science version 25 for further analysis. Both bi-variable and multivariable logistic regression analysis were done to identify the determinants and a p-value < 0.05 with a 95% confidence level was used to declare statistical significance.
Being an urban dweller (AOR = 2.1, 95% CI: 1.01, 4.34), having polygamous husband (AOR = 2.92, 95% CI: 1.27, 6.68), having history asthma/ other respiratory tract infections (AOR = 3.56, 95% CI: 1.43, 8.82), saturated fat intake (AOR = 4.06 95% CI: 1.98, 8.3), no intake of ginger (AOR = 3.04 95% CI: 1.14, 8.09), and inadequate intake of vitamin B rich foods (2.2, 95% CI: 1.14-4.2) were the determinants of hyperemesis gravidarum.
This study revealed that, urban residence, having polygamous husband, history of asthma/other respiratory tract infections, intake of saturated fat, no intake of ginger, inadequate intake of vitamin B reach foods were found to be independent determinants of hyperemesis gravidarum. It is better if healthcare providers and government authorities exert continual effort to give health education and counselling service concerning to dietary practice and asthma attacks. It is advisable if pregnant women adhere to healthy diets and limit intake of saturated fats and also husband and nearby relatives give care and support for pregnant women.
妊娠剧吐是一种严重的恶心和过度呕吐,始于妊娠 4-6 周,高峰在妊娠 8-12 周,通常在 20 周时缓解和消退。确定妊娠剧吐的决定因素对于早期发现和干预以减少健康、心理社会和经济影响具有特别重要的意义。在埃塞俄比亚,关于妊娠剧吐决定因素的信息很少。
本研究采用 2021 年 4 月 12 日至 6 月 12 日进行的基于机构的病例对照研究设计。使用结构化的面对面访谈员管理问卷和文件审查清单,从 360 名研究参与者(120 例病例和 240 例对照)中收集数据。数据由 KoBocollect 1.3 收集,然后导出到统计软件包 25 进行进一步分析。进行了双变量和多变量逻辑回归分析,以确定决定因素,p 值<0.05,置信水平为 95%,用于宣布统计学意义。
城市居民(AOR=2.1,95%CI:1.01,4.34)、一夫多妻的丈夫(AOR=2.92,95%CI:1.27,6.68)、哮喘/其他呼吸道感染史(AOR=3.56,95%CI:1.43,8.82)、饱和脂肪摄入(AOR=4.06,95%CI:1.98,8.3)、不摄入生姜(AOR=3.04,95%CI:1.14,8.09)和维生素 B 丰富食物摄入不足(2.2,95%CI:1.14-4.2)是妊娠剧吐的决定因素。
本研究表明,城市居住、一夫多妻的丈夫、哮喘/其他呼吸道感染史、饱和脂肪摄入、不摄入生姜、维生素 B 丰富食物摄入不足与妊娠剧吐有关。卫生保健提供者和政府当局最好继续努力,提供有关饮食实践和哮喘发作的健康教育和咨询服务。建议孕妇坚持健康饮食,限制饱和脂肪摄入,丈夫和附近亲属给予孕妇关怀和支持。