Reynaud A E, Espaze E P, Courtieu A L
Pathol Biol (Paris). 1986 Dec;34(10):1091-5.
The activity of different antibiotics was considered by studying the results reported in literature and during the IXth International Symposium on the Problems of Listeriosis. Listeria susceptibility to antibiotics did not change. Ampicillin was always one of the most effective and used antibiotics against Listeria. The association with an aminoglycoside produced a synergistic effect, which made the bactericidal activity quicker, in vitro as in vivo on animal. More recent molecules like third generation cephalosporins or fluoro-piperazinyl-quinolones had poor activity against Listeria.
通过研究文献报道的结果以及在第九届李斯特菌病问题国际研讨会上所呈现的结果,来考量不同抗生素的活性。李斯特菌对抗生素的敏感性并未改变。氨苄西林一直是对抗李斯特菌最有效的常用抗生素之一。与氨基糖苷类药物联合使用会产生协同效应,这使得杀菌活性在体外以及对动物体内实验中都变得更快。像第三代头孢菌素或氟哌嗪基喹诺酮类等更新的分子对李斯特菌的活性较差。