Kemnitz J W, Francken G A
Physiol Behav. 1986 Oct;38(4):477-83. doi: 10.1016/0031-9384(86)90414-2.
Adult male rhesus monkeys representing a wide range of adiposity were characterized according to body dimensions, eating behaviors, and endocrinologic/metabolic indices. Body fat, located most prominently on the abdomen, ranged from 30 to 61% of body weight. Three groups were formed on the basis of body composition data: Very Obese (VO), Moderately Obese (MO) and Nonobese (N). These groups did not differ in food intake, preferences for sweet solutions, or compensatory changes in food intake following consumption of sugar solutions. Glucose tolerance was normal, but fasting insulin levels and insulin response to glucose loading increased with increasing adiposity. Fasting triglyceride levels were highly correlated with insulin values and body fat. It is concluded that some adult male rhesus monkeys develop obesity without obvious differences in eating behavior and that obese monkeys, like obese humans, are at risk for diabetes mellitus and its complications.
根据身体尺寸、进食行为以及内分泌/代谢指标，对代表不同肥胖程度的成年雄性恒河猴进行了特征描述。身体脂肪主要集中在腹部，占体重的30%至61%。根据身体成分数据分为三组：极肥胖组（VO）、中度肥胖组（MO）和非肥胖组（N）。这些组在食物摄入量、对甜味溶液的偏好或饮用糖溶液后食物摄入量的代偿性变化方面没有差异。葡萄糖耐量正常，但空腹胰岛素水平以及对葡萄糖负荷的胰岛素反应随着肥胖程度的增加而升高。空腹甘油三酯水平与胰岛素值和身体脂肪高度相关。得出的结论是，一些成年雄性恒河猴在没有明显进食行为差异的情况下出现肥胖，并且肥胖的猴子与肥胖的人类一样，有患糖尿病及其并发症的风险。
