Elbadry Mohamed S, Ali Ahmed Issam, Hassan Ali, Clement Kieran David, Hammady Ahmed Rashed, Abdbelaal Abdalla, Barsoum Nady Mounir, Hassan Mohamed Abd Elmalek, Gabr Ahmed H
Department of Urology Minia University Minia Egypt.
NHS Greater Glasgow and Clyde (NHSGGC) Glasgow UK.
BJUI Compass. 2020 Jun 19;1(4):133-138. doi: 10.1002/bco2.29. eCollection 2020 Sep.
We aimed to compare health-related quality of life (HrQoL) in patients who underwent ileal conduit (IC) vs orthotopic neobladder (ONB) as a method of urinary diversion (UD) after radical cystectomy (RC) for invasive bladder cancers.
The questionnaires of the Functional Assessment of Cancer Therapy-Bladder Cancer (FACT-BL) were used to evaluate and compare the HrQoL in 113 patients with 1 year follow-up.
Forty-nine patients were included in the ONB group and 64 patients in the IC group. Patients with IC showed superior scores in all domains of the FACT-BL questionnaire and this reached statistical significance in physical well-being (PWB), functional well-being (FWB), over all FACT-G, Bladder-Specific Subscale and FACT-BL total scores (-values = .01, .01, .001, .001, and .001, respectively).
Our findings demonstrate marginally improved HrQoL in IC patients when compared with patients undergoing ONB which may be attributed to an increased morbidity and postoperative complications in the ONB group.
我们旨在比较接受回肠膀胱术（IC）与原位新膀胱术（ONB）作为浸润性膀胱癌根治性膀胱切除术（RC）后尿流改道（UD）方法的患者的健康相关生活质量（HrQoL）。
使用癌症治疗功能评估-膀胱癌（FACT-BL）问卷对113例患者进行为期1年的随访，以评估和比较HrQoL。
ONB组纳入49例患者，IC组纳入64例患者。IC组患者在FACT-BL问卷的所有领域得分均更高，在身体健康（PWB）、功能健康（FWB）、总体FACT-G、膀胱特异性子量表和FACT-BL总分方面达到统计学意义（P值分别为0.01、0.01、0.001、0.001和）。
我们的研究结果表明，与接受ONB的患者相比，IC患者的HrQoL略有改善，这可能归因于ONB组发病率和术后并发症增加。
