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一名慢性淋巴细胞白血病患者因严重中性粒细胞减少和淋巴细胞减少,感染嗜水气单胞菌导致社区获得性细菌性肺炎并伴有感染性休克。

Aeromonas hydrophila Community-Acquired Bacterial Pneumonia With Septic Shock in a Chronic Lymphocytic Leukemia Patient Due to Absolute Neutropenia and Lymphopenia.

作者信息

Patil Sachin M, Hilker Eric D

机构信息

Infectious Disease and Critical Care, University of Missouri Health Care, Columbia, USA.

Internal Medicine, University of Missouri School of Medicine, Columbia, USA.

出版信息

Cureus. 2022 Mar 20;14(3):e23345. doi: 10.7759/cureus.23345. eCollection 2022 Mar.

Abstract

is a gram-negative (GN) bacillus with an opportunistic potential in immunocompromised patients. They are ubiquitary in fresh and brackish water capable of infecting healthy and immunosuppressed patients. Clinical manifestations vary in healthy hosts compared to immunocompromised patients. Community-acquired bacterial pneumonia (CABP) is an infrequent clinical presentation of infection, even in immunosuppressed patients. It is also an uncommon cause of nosocomial and drowning-related pneumonia. Although a rare cause of CABP, the clinical course is fulminant with higher mortality due to lower clinical suspicion. Here, we present an immunocompromised 63-year-old Caucasian male with chronic lymphocytic leukemia (CLL) presenting with acute CABP with septic shock due to absolute neutropenia and lymphopenia.

摘要

是一种革兰氏阴性(GN)杆菌,在免疫功能低下的患者中具有机会致病潜力。它们广泛存在于淡水和微咸水中,能够感染健康人和免疫抑制患者。与免疫功能低下的患者相比,健康宿主中的临床表现有所不同。社区获得性细菌性肺炎(CABP)即使在免疫抑制患者中也是感染的不常见临床表现。它也是医院获得性肺炎和溺水相关性肺炎的罕见病因。尽管是CABP的罕见病因,但由于临床怀疑较低,临床病程凶险,死亡率较高。在此,我们报告一名63岁患有慢性淋巴细胞白血病(CLL)的免疫功能低下的白种男性,因绝对中性粒细胞减少和淋巴细胞减少而出现急性CABP并伴有感染性休克。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/299d/9018926/77ac578ad7af/cureus-0014-00000023345-i01.jpg

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