Universidade de São Paulo, Faculdade de Odontologia de Ribeirão Preto, Departamento de Odontopediatria, Ribeirão Preto, São Paulo, Brasil.
Universidade de São Paulo, Ribeirão Preto, Escola de Ciências Farmacêuticas de Ribeirão Preto São Paulo, Departamento de Ciências Farmacêuticas, Brasil.
J Appl Oral Sci. 2022 Apr 20;30:e20210538. doi: 10.1590/1678-7757-2021-0538. eCollection 2022.
Molar incisor hypomineralization (MIH) is often accompanied by dental hypersensitivity and difficulty in achieving effective analgesia.
This study evaluated the effectiveness of preemptive analgesia in children with severe MIH, post-eruptive enamel breakdown, and hypersensitivity.
Ibuprofen (10 mg/kg child weight) or placebo was administered, followed by infiltrative anesthesia and restoration with resin composite. Hypersensitivity was evaluated in five moments. The data were analyzed using the chi-square test, Fisher's exact test, and t-test.
Preemptive analgesia provided benefits for the treatment of severe cases of MIH, with an increase in the effectiveness of infiltrative anesthesia and improved patient comfort during the restorative procedure.
Preemptive analgesia has shown efficacy in reducing hypersensitivity during restorative dental procedures, evidencing the significance of this study for patients with MIH and hypersensitivity.
磨牙-切牙牙釉质发育不全（MIH）常伴有牙齿过敏和难以达到有效镇痛。
本研究评估了预防性镇痛在伴有釉质萌出后破裂和过敏的严重 MIH 儿童中的有效性。
给予布洛芬（10mg/kg 儿童体重）或安慰剂，然后进行浸润麻醉和树脂复合材料修复。在五个时刻评估过敏情况。使用卡方检验、Fisher 确切检验和 t 检验分析数据。
预防性镇痛对治疗严重 MIH 病例有效，增加了浸润麻醉的效果，并在修复过程中提高了患者舒适度。
预防性镇痛在减少修复性牙科治疗中的过敏方面显示出有效性，证明了这项针对 MIH 和过敏患者的研究的重要性。
