Department of Dentistry-Oral Health Institute, Hamad Medical Corporation, Doha, Qatar; College of Dental Medicine, Qatar University, Doha, Qatar.
Dental Health Department, College of Applied Medical Sciences, King Saud University, P.O. Box 10219, Riyadh, 11433, Saudi Arabia.
Photodiagnosis Photodyn Ther. 2022 Sep;39:102882. doi: 10.1016/j.pdpdt.2022.102882. Epub 2022 Apr 25.
reExtensive rsearch has been done on various disinfection modalities used to achieve an aseptic implant surface. However, the bacterial efficacy and the topographical alterations resulting from the use of these techniques have never been compared.
This study aimed to evaluate and compare the disinfection efficacy and surface changes on a bacteria contaminated titanium block following application of various disinfectants.
Ultrasonically cleaned titanium blocks were contaminated with Porphyromonas gingivalis and Tannerella forsythia. The infected titanium implants were randomly divided into four experimental groups and decontaminated using antimicrobial photodynamic therapy (aPDT), laser therapy, chlorhexidine and hydrogen peroxide. Bacterial viability and surface changes following decontamination were analyzed.
Bacterial viability decreased in all the groups, with aPDT having the highest reduction. Surface roughness remained unchanged whereas the contact angle lessened in the aPDT group.
aPDT could possibly be a suitable alternative to other disinfection regimen to treat periimplantitis.
已经对用于实现无菌植入物表面的各种消毒方式进行了广泛的研究。然而，这些技术的细菌功效和表面形貌改变效果从未被比较过。
本研究旨在评估和比较各种消毒剂应用于污染的钛块后，在细菌污染的钛块上的消毒效果和表面变化。
将经过超声清洗的钛块用牙龈卟啉单胞菌和福赛斯坦纳菌进行污染。受感染的钛植入物被随机分为四个实验组，分别使用抗菌光动力疗法（aPDT）、激光治疗、洗必泰和过氧化氢进行消毒。分析消毒后的细菌活力和表面变化。
所有组的细菌活力均降低，aPDT 组的降低幅度最大。表面粗糙度保持不变，而 aPDT 组的接触角减小。
aPDT 可能是治疗种植体周围炎的其他消毒方案的合适替代方案。
