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COVID-19 相关腮腺脓肿。

COVID-19-associated Parotid Gland Abscess.

机构信息

Oral and Craniomaxillofacial Surgery, Eppendorf University Hospital, University of Hamburg, Hamburg, Germany.

出版信息

In Vivo. 2022 May-Jun;36(3):1349-1353. doi: 10.21873/invivo.12837.

DOI:10.21873/invivo.12837
PMID:35478161
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9087059/
Abstract

BACKGROUND

Human infection with the SARS-CoV-2 virus has caused a pandemic characterized by a plethora of diseases, of which those affecting the internal organs and nervous system can have severe, life-threatening consequences. Among the manifestations of the disease at the viral entry site, diseases in oral mucosa adnexa are rarely reported. This case report describes a COVID-19-associated aggravating parotid gland disease.

CASE REPORT

The 47-year-old, SARS-CoV-2-positive male patient, already hospitalized and now in need of ventilation, had been referred for intensive care treatment due to increasing respiratory problems. A unilateral swelling of the cheek was noticed, the cause of which was initially a parotid gland infection. Examination ruled out mechanical causes of the parotid gland. During further treatment, the patient developed a parotid abscess, which was drained extra orally.

CONCLUSION

The oral cavity is primarily considered as a reservoir of the pathogen. There is an increasing number of reports detailing inflammation of the major salivary glands associated with SARS-CoV-2 virus. Knowledge of this association facilitates therapeutic decisions.

摘要

背景

人类感染 SARS-CoV-2 病毒引发了一场大流行,其特征是出现大量疾病,其中影响内脏和神经系统的疾病可能会产生严重的、危及生命的后果。在病毒进入部位的疾病表现中,口腔黏膜附属器疾病很少见。本病例报告描述了一例与 COVID-19 相关的、使腮腺疾病恶化的病例。

病例报告

该 47 岁男性 SARS-CoV-2 阳性患者已住院,现需通气治疗,因呼吸问题加重而被转至重症监护治疗。患者出现单侧脸颊肿胀,最初被诊断为腮腺感染。检查排除了腮腺机械性原因。在进一步治疗过程中,患者发展为腮腺脓肿,行口腔外引流。

结论

口腔主要被认为是病原体的储存库。越来越多的报告详细描述了与 SARS-CoV-2 病毒相关的主要唾液腺炎症。了解这种关联有助于做出治疗决策。

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ACE2 and TMPRSS2 in human saliva can adsorb to the oral mucosal epithelium.人唾液中的 ACE2 和 TMPRSS2 可以吸附到口腔黏膜上皮。
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Multisystemic Cellular Tropism of SARS-CoV-2 in Autopsies of COVID-19 Patients.COVID-19 患者尸检中 SARS-CoV-2 的多系统细胞嗜性。
Cells. 2021 Jul 27;10(8):1900. doi: 10.3390/cells10081900.
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Oral Manifestations in Patients with COVID-19: A 6-Month Update.《COVID-19 患者的口腔表现:6 个月更新》。
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Acute parotitis in a 4-year-old in association with COVID-19.一名4岁儿童患急性腮腺炎并伴有新型冠状病毒肺炎。
J Paediatr Child Health. 2021 Jun;57(6):958-959. doi: 10.1111/jpc.15527. Epub 2021 Apr 28.
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J Pathol. 2021 Jul;254(3):239-243. doi: 10.1002/path.5679. Epub 2021 May 21.
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SARS-CoV-2 infection of the oral cavity and saliva.SARS-CoV-2 对口腔和唾液的感染。
Nat Med. 2021 May;27(5):892-903. doi: 10.1038/s41591-021-01296-8. Epub 2021 Mar 25.
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J Dent Res. 2021 May;100(5):464-471. doi: 10.1177/0022034521997112. Epub 2021 Mar 3.
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