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新冠感染后口干、味觉和嗅觉损伤的评估。

Evaluation of the xerostomia, taste and smell impairments after Covid-19.

机构信息

Ordu University, Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Altınordu/Ordu, 52200, Turkey

出版信息

Med Oral Patol Oral Cir Bucal. 2021 Sep 1;26(5):e568-e575. doi: 10.4317/medoral.24510.

Abstract

BACKGROUND

The purpose of this study was to explore the effects of coronavirus disease 19 (Covid-19) on the oral cavity by evaluating the oral findings in the patients who recovered after treatment.

MATERIAL AND METHODS

This study involved confirmed Covid-19 patients whose treatment completed at least two weeks ago. A questionnaire consist of eight parts was applied to explore the oral findings after Covid-19. Also stimulated salivary flow rate was evaluated with a salivary flow test.

RESULTS

177 patients reached and 107 of them participate in the study. Regarding gender significant differences were found in terms of the presence of taste impairment after treatment (p=0.007), the degree of taste (p=0.021) and smell (p=0.010) impairment. 18 % (5/27) of the patients evaluated were showed hyposalivation. No significant differences were observed regarding salivary flow between males (mean±SD: 1.14±0.65) and females (mean±SD: 1.12±0.43), (p=0.928); among the patients having treatment at home (mean±SD: 1.03±0.48) or hospital (mean±SD: 1.33±0.65), (p=0.187). In some of the patients' taste [15], smell [23] impairment, and xerostomia [43] still observed at least two weeks after the treatment is completed.

CONCLUSIONS

The most frequent finding in patients after the treatment was xerostomia. Taste and smell impairments were more frequently observed in females.

摘要

背景

本研究旨在通过评估治疗后康复患者的口腔发现来探讨 2019 年冠状病毒病(Covid-19)对口腔的影响。

材料与方法

本研究纳入了治疗完成至少两周的确诊 Covid-19 患者。采用包含八个部分的问卷来探讨新冠感染后口腔发现。还通过唾液流率测试评估了刺激唾液流率。

结果

共有 177 名患者达到标准,其中 107 名患者参与了研究。在治疗后味觉障碍的出现(p=0.007)、味觉(p=0.021)和嗅觉(p=0.010)障碍程度方面,性别存在显著差异。18%(5/27)的患者出现低分泌。男性(均值±标准差:1.14±0.65)和女性(均值±标准差:1.12±0.43)唾液流率之间无显著差异(p=0.928);在家(均值±标准差:1.03±0.48)或医院(均值±标准差:1.33±0.65)接受治疗的患者之间也无显著差异(p=0.187)。在一些患者中,治疗完成至少两周后仍观察到味觉[15]、嗅觉[23]障碍和口干[43]。

结论

治疗后患者最常见的发现是口干。女性更常出现味觉和嗅觉障碍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/658e/8412452/2c61e46dd5ad/medoral-26-e568-g001.jpg

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