Laboratory of Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Leuven, Belgium.
Microb Biotechnol. 2022 Jul;15(7):1940-1942. doi: 10.1111/1751-7915.14065. Epub 2022 Apr 27.
Based on archived medical records and evolutionary modelling, a Coronavirus has been hypothesized as root and causative agent of the so-called 'Russian Flu' pandemic that surged in 1889-1890. In a Correspondence published in this volume of Microbial Biotechnology, Ramassy and colleagues try to support historical evidence by true experimental data using 'palaeoserology', a novel approach combining archaeology and modern immunological analysis. This Opinion piece tries to weigh arguments how strong such data may be, and where a refinement of methodology might be desirable before textbooks of medical history switch to call the 1890s pandemic 'Russian Corona'.
基于存档的医学记录和进化建模,一种冠状病毒被假设为所谓的“俄罗斯流感”大流行的根源和病原体,该大流行在 1889-1890 年爆发。在本期《微生物生物技术》杂志上发表的一封通讯中,Ramassy 及其同事试图通过使用“古血清学”的真正实验数据来支持历史证据,这是一种结合考古学和现代免疫分析的新方法。这篇观点文章试图权衡这些数据的可靠性,以及在医学史教科书将 19 世纪 90 年代的大流行称为“俄罗斯冠状病毒”之前,在方法学上进行改进的必要性。