Hendy Jessica
BioArCh, Department of Archaeology, University of York, York, UK.
Max Planck Institute for the Science of Human History, Jena, Germany. Email:
Sci Adv. 2021 Jan 15;7(3). doi: 10.1126/sciadv.abb9314. Print 2021 Jan.
The analysis of ancient proteins from paleontological, archeological, and historic materials is revealing insights into past subsistence practices, patterns of health and disease, evolution and phylogeny, and past environments. This review tracks the development of this field, discusses some of the major methodological strategies used, and synthesizes recent developments in archeological applications of ancient protein analysis. Moreover, this review highlights some of the challenges faced by the field and potential future directions, arguing that the development of minimally invasive or nondestructive techniques, strategies for protein authentication, and the integration of ancient protein analysis with other biomolecular techniques are important research strategies as this field grows.
对来自古生物学、考古学和历史材料的古代蛋白质进行分析，正在揭示有关过去生存方式、健康与疾病模式、进化与系统发育以及过去环境的见解。本综述追踪了该领域的发展，讨论了一些主要使用的方法策略，并综合了古代蛋白质分析在考古应用中的最新进展。此外，本综述强调了该领域面临的一些挑战和潜在的未来方向，认为随着该领域的发展，开发微创或非破坏性技术、蛋白质鉴定策略以及将古代蛋白质分析与其他生物分子技术相结合是重要的研究策略。
